ZFIN is now using GRCz12tu for Genomic Data
Gene
sco1
- ID
- ZDB-GENE-140909-1
- Name
- synthesis of cytochrome C oxidase 1
- Symbol
- sco1 Nomenclature History
- Previous Names
- None
- Type
- protein_coding_gene
- Location
- Chr: 3 Mapping Details/Browsers
- Genome Assembly
- GRCz12tu
- Annotation Status
- Current
- Description
- Predicted to enable metal ion binding activity. Predicted to be involved in mitochondrial respiratory chain complex IV assembly. Predicted to be located in mitochondrial inner membrane. Human ortholog(s) of this gene implicated in cytochrome-c oxidase deficiency disease and mitochondrial complex IV deficiency nuclear type 4. Orthologous to human SCO1 (synthesis of cytochrome C oxidase 1).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 2 figures from 2 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| mitochondrial complex IV deficiency nuclear type 4 | Alliance | Mitochondrial complex IV deficiency, nuclear type 4 | 619048 |
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Additional Resources | Length | Copper chaperone SCO1/SenC | Thioredoxin-like superfamily |
|---|---|---|---|---|
| UniProtKB:E7FD19 | InterPro | 318 |
- Genome Browsers
Interactions and Pathways
No data available
Plasmids
No data available
- Genome Browsers