Gene
dync2i1
- ID
- ZDB-GENE-140821-1
- Name
- dynein 2 intermediate chain 1
- Symbol
- dync2i1 Nomenclature History
- Previous Names
-
- wdr60
- Type
- protein_coding_gene
- Location
- Chr: 7 Mapping Details/Browsers
- Description
- Predicted to enable dynein heavy chain binding activity and dynein light chain binding activity. Predicted to act upstream of or within intraciliary transport. Predicted to be part of cytoplasmic dynein complex. Human ortholog(s) of this gene implicated in short-rib thoracic dysplasia 8 with or without polydactyly. Orthologous to human DYNC2I1 (dynein 2 intermediate chain 1).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- No data available
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| short-rib thoracic dysplasia 8 with or without polydactyly | Alliance | Short-rib thoracic dysplasia 8 with or without polydactyly | 615503 |
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Length | Cytoplasmic dynein 2 intermediate chain 1 | WD40 repeat | WD40-repeat-containing domain superfamily | WD40/YVTN repeat-like-containing domain superfamily |
|---|---|---|---|---|---|
|
UniProtKB:A0A8M1RKA7
|
1049 | ||||
|
UniProtKB:A0A1D5NS24
|
1047 | ||||
|
UniProtKB:A0A8M2BDV9
|
1031 | ||||
|
UniProtKB:A0A8M2BDY7
|
1026 |
Interactions and Pathways
No data available
Plasmids
No data available