Gene
mhc1lca
- ID
- ZDB-GENE-140820-4
- Name
- major histocompatibility complex class I LCA
- Symbol
- mhc1lca Nomenclature History
- Previous Names
-
- sb:eu2458
- si:dkey-225f5.5
- Type
- protein_coding_gene
- Location
- Chr: 3 Mapping Details/Browsers
- Description
- Predicted to be located in membrane. Human ortholog(s) of this gene implicated in pulmonary tuberculosis. Orthologous to several human genes including CD1A (CD1a molecule); CD1B (CD1b molecule); and CD1C (CD1c molecule).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 1 figure from Thisse et al., 2005
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- eu2458 (1 image)
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Conserved_site | IPR003006 | Immunoglobulin/major histocompatibility complex, conserved site |
| Domain | IPR003597 | Immunoglobulin C1-set |
| Domain | IPR007110 | Immunoglobulin-like domain |
| Domain | IPR011161 | MHC class I-like antigen recognition-like |
| Family | IPR050208 | Antigen-presenting and immune regulatory MHC class I-related |
| Homologous_superfamily | IPR011162 | MHC classes I/II-like antigen recognition protein |
| Homologous_superfamily | IPR013783 | Immunoglobulin-like fold |
| Homologous_superfamily | IPR036179 | Immunoglobulin-like domain superfamily |
| Homologous_superfamily | IPR037055 | MHC class I-like antigen recognition-like superfamily |
Domain Details Per Protein
| Protein | Additional Resources | Length | Antigen-presenting and immune regulatory MHC class I-related | Immunoglobulin C1-set | Immunoglobulin-like domain | Immunoglobulin-like domain superfamily | Immunoglobulin-like fold | Immunoglobulin/major histocompatibility complex, conserved site | MHC classes I/II-like antigen recognition protein | MHC class I-like antigen recognition-like | MHC class I-like antigen recognition-like superfamily |
|---|---|---|---|---|---|---|---|---|---|---|---|
| UniProtKB:A0A8M9PDN6 | InterPro | 356 | |||||||||
| UniProtKB:A0A0R4IZK4 | InterPro | 350 |
| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA |
si:dkey-225f5.5-201
(1)
|
Ensembl | 1,663 nt |
Interactions and Pathways
No data available
Plasmids
No data available