Gene
dsg2.2
- ID
- ZDB-GENE-140723-1
- Name
- desmoglein 2, tandem duplicate 2
- Symbol
- dsg2.2 Nomenclature History
- Previous Names
-
- CABZ01055869.1 (1)
- zmp:0000001074
- Type
- protein_coding_gene
- Location
- Chr: 20 Mapping Details/Browsers
- Description
- Predicted to enable calcium ion binding activity. Predicted to be involved in cell-cell junction organization and epiboly involved in gastrulation with mouth forming second. Predicted to act upstream of or within homophilic cell adhesion via plasma membrane adhesion molecules. Predicted to be located in desmosome and plasma membrane.
- Genome Resources
-
- Alliance (1)
- Gene:101882022 (1)
- Note
-
This gene corresponds to ENSDARG00000039665 in ensembl
- Comparative Information
-
- All Expression Data
- No data available
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| arrhythmogenic right ventricular dysplasia 10 | Alliance | Arrhythmogenic right ventricular dysplasia 10 | 610193 |
| dilated cardiomyopathy 1BB | Alliance | Cardiomyopathy, dilated, 1BB | 612877 |
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Conserved_site | IPR020894 | Cadherin conserved site |
| Domain | IPR000233 | Cadherin, Y-type LIR-motif |
| Domain | IPR002126 | Cadherin-like |
| Family | IPR009122 | Desmosomal cadherin |
| Family | IPR050971 | Cadherin domain-containing protein |
| Homologous_superfamily | IPR015919 | Cadherin-like superfamily |
| Homologous_superfamily | IPR027397 | Catenin binding domain superfamily |
Domain Details Per Protein
| Protein | Additional Resources | Length | Cadherin conserved site | Cadherin domain-containing protein | Cadherin-like | Cadherin-like superfamily | Cadherin, Y-type LIR-motif | Catenin binding domain superfamily | Desmosomal cadherin |
|---|---|---|---|---|---|---|---|---|---|
| UniProtKB:A0A8M9PT78 | InterPro | 1418 |
- Genome Browsers
Interactions and Pathways
No data available
Plasmids
No data available
- Comparative Orthology
- Alliance