Gene
kcnab2a
- ID
- ZDB-GENE-140515-2
- Name
- potassium voltage-gated channel subfamily A regulatory beta subunit 2a
- Symbol
- kcnab2a Nomenclature History
- Previous Names
- None
- Type
- protein_coding_gene
- Location
- Chr: 11 Mapping Details/Browsers
- Description
- Predicted to enable aldo-keto reductase (NADPH) activity; potassium channel regulator activity; and transmembrane transporter binding activity. Predicted to be involved in regulation of potassium ion transmembrane transport. Predicted to act upstream of or within monoatomic ion transmembrane transport and potassium ion transport. Predicted to be located in several cellular components, including axon; cytoskeleton; and synapse. Predicted to be part of voltage-gated potassium channel complex. Predicted to be active in juxtaparanode region of axon. Orthologous to human KCNAB2 (potassium voltage-gated channel subfamily A regulatory beta subunit 2).
- Genome Resources
- Note
-
this gene corresponds to ENSDARG00000087247. No other sequence is currently available.
- Comparative Information
-
- All Expression Data
- 1 figure from Watanabe et al., 2014
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Domain | IPR023210 | NADP-dependent oxidoreductase domain |
| Family | IPR005399 | Potassium channel, voltage-dependent, beta subunit, KCNAB-related |
| Family | IPR005400 | Potassium channel, voltage-dependent, beta subunit, KCNAB1 |
| Family | IPR005401 | Potassium channel, voltage-dependent, beta subunit, KCNAB2 |
| Family | IPR005983 | Potassium channel, voltage-dependent, beta subunit, KCNAB |
| Homologous_superfamily | IPR036812 | NADP-dependent oxidoreductase domain superfamily |
Domain Details Per Protein
| Protein | Length | NADP-dependent oxidoreductase domain | NADP-dependent oxidoreductase domain superfamily | Potassium channel, voltage-dependent, beta subunit, KCNAB | Potassium channel, voltage-dependent, beta subunit, KCNAB1 | Potassium channel, voltage-dependent, beta subunit, KCNAB2 | Potassium channel, voltage-dependent, beta subunit, KCNAB-related |
|---|---|---|---|---|---|---|---|
|
UniProtKB:A0A8M3BDW0
|
367 | ||||||
|
UniProtKB:A0A8M3B738
|
353 | ||||||
|
UniProtKB:A0A8M9QM51
|
430 | ||||||
|
UniProtKB:A0A8M3AXY2
|
397 |
| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA |
kcnab2a-201
(1)
|
Ensembl | 1,587 nt | ||
| mRNA |
kcnab2a-202
(1)
|
Ensembl | 1,708 nt |
Interactions and Pathways
No data available
Plasmids
No data available
- Comparative Orthology
- Alliance