Gene
prkg1l
- ID
- ZDB-GENE-140422-2
- Name
- protein kinase cGMP-dependent 1, like
- Symbol
- prkg1l Nomenclature History
- Previous Names
- None
- Type
- protein_coding_gene
- Location
- Chr: 8 Mapping Details/Browsers
- Description
- Human ortholog(s) of this gene implicated in thoracic aortic aneurysm. Orthologous to human PRKG1 (protein kinase cGMP-dependent 1).
- Genome Resources
-
- Alliance (1)
- Gene:100535807 (1)
- Note
-
This gene corresponds to ENSDARG00000068026 ; Chr8. NCBI: XM_003199149.2
- Comparative Information
-
- All Expression Data
- No data available
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| thoracic aortic aneurysm | Alliance | Aortic aneurysm, familial thoracic 8 | 615436 |
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Active_site | IPR008271 | Serine/threonine-protein kinase, active site |
| Binding_site | IPR017441 | Protein kinase, ATP binding site |
| Domain | IPR000595 | Cyclic nucleotide-binding domain |
| Domain | IPR000719 | Protein kinase domain |
| Domain | IPR000961 | AGC-kinase, C-terminal |
| Family | IPR002374 | cGMP-dependent kinase |
| Homologous_superfamily | IPR011009 | Protein kinase-like domain superfamily |
| Homologous_superfamily | IPR014710 | RmlC-like jelly roll fold |
| Homologous_superfamily | IPR018490 | Cyclic nucleotide-binding domain superfamily |
Domain Details Per Protein
| Protein | Length | AGC-kinase, C-terminal | cGMP-dependent kinase | Cyclic nucleotide-binding domain | Cyclic nucleotide-binding domain superfamily | Protein kinase, ATP binding site | Protein kinase domain | Protein kinase-like domain superfamily | RmlC-like jelly roll fold | Serine/threonine-protein kinase, active site |
|---|---|---|---|---|---|---|---|---|---|---|
|
UniProtKB:A0A8M9PRK8
|
659 | |||||||||
|
UniProtKB:A0A8M6Z2D7
|
681 |
- Genome Browsers
Interactions and Pathways
No data available
Plasmids
No data available
- Comparative Orthology
- Alliance