Gene
zmp:0000001138
- ID
- ZDB-GENE-140106-98
- Name
- zmp:0000001138
- Symbol
- zmp:0000001138 Nomenclature History
- Previous Names
- None
- Type
- protein_coding_gene
- Location
- Chr: 13 Mapping Details/Browsers
- Description
- Predicted to be involved in antigen processing and presentation of peptide antigen via MHC class I and immune response. Predicted to localize to MHC class I protein complex; extracellular region; and integral component of membrane. Human ortholog(s) of this gene implicated in arthritis; familial visceral amyloidosis; inflammatory bowel disease; and primary immunodeficiency disease. Orthologous to human B2M (beta-2-microglobulin).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- No data available
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Conserved_site | IPR003006 | Immunoglobulin/major histocompatibility complex, conserved site |
| Domain | IPR003597 | Immunoglobulin C1-set |
| Domain | IPR007110 | Immunoglobulin-like domain |
| Family | IPR015707 | Beta-2-Microglobulin |
| Family | IPR050160 | Major Histocompatibility Complex/Immunoglobulin |
| Homologous_superfamily | IPR013783 | Immunoglobulin-like fold |
| Homologous_superfamily | IPR036179 | Immunoglobulin-like domain superfamily |
Domain Details Per Protein
| Protein | Length | Beta-2-Microglobulin | Immunoglobulin C1-set | Immunoglobulin-like domain | Immunoglobulin-like domain superfamily | Immunoglobulin-like fold | Immunoglobulin/major histocompatibility complex, conserved site | Major Histocompatibility Complex/Immunoglobulin |
|---|---|---|---|---|---|---|---|---|
|
UniProtKB:A4JYR1
|
250 |
- Genome Browsers
| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA |
zmp:0000001138-201
(1)
|
Ensembl | 3,701 nt |
Interactions and Pathways
No data available
Plasmids
No data available
- Comparative Orthology
- Alliance