Gene
st14
- ID
- ZDB-GENE-140106-74
- Name
- ST14 transmembrane serine protease matriptase
- Symbol
- st14 Nomenclature History
- Previous Names
-
- zmp:0000001114 (1)
- Type
- protein_coding_gene
- Location
- Chr: 15 Mapping Details/Browsers
- Description
- Predicted to have serine-type endopeptidase activity. Predicted to be involved in proteolysis. Predicted to localize to integral component of membrane. Human ortholog(s) of this gene implicated in autosomal recessive congenital ichthyosis 11. Orthologous to human ST14 (suppression of tumorigenicity 14).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- No data available
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Active_site | IPR033116 | Serine proteases, trypsin family, serine active site |
| Conserved_site | IPR023415 | Low-density lipoprotein (LDL) receptor class A, conserved site |
| Domain | IPR000082 | SEA domain |
| Domain | IPR000859 | CUB domain |
| Domain | IPR001254 | Serine proteases, trypsin domain |
| Homologous_superfamily | IPR009003 | Peptidase S1, PA clan |
| Homologous_superfamily | IPR035914 | Spermadhesin, CUB domain superfamily |
| Homologous_superfamily | IPR036055 | LDL receptor-like superfamily |
| Homologous_superfamily | IPR036364 | SEA domain superfamily |
| Homologous_superfamily | IPR043504 | Peptidase S1, PA clan, chymotrypsin-like fold |
| Repeat | IPR002172 | Low-density lipoprotein (LDL) receptor class A repeat |
Domain Details Per Protein
| Protein | Length | CUB domain | LDL receptor-like superfamily | Low-density lipoprotein (LDL) receptor class A, conserved site | Low-density lipoprotein (LDL) receptor class A repeat | Peptidase S1, PA clan | Peptidase S1, PA clan, chymotrypsin-like fold | SEA domain | SEA domain superfamily | Serine proteases, trypsin domain | Serine proteases, trypsin family, serine active site | Spermadhesin, CUB domain superfamily |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
|
UniProtKB:H9GXL1
|
841 |
- Genome Browsers
Interactions and Pathways
No data available
Plasmids
No data available