Gene

si:ch211-122f10.4

ID

ZDB-GENE-140106-45

Name

si:ch211-122f10.4

Symbol

si:ch211-122f10.4 Nomenclature History

Previous Names

zmp:0000001085 (1)

Type

protein_coding_gene

Location

Chr: 7 Mapping Details/Browsers

Description

Predicted to enable serine-type carboxypeptidase activity. Predicted to act upstream of or within proteolysis.

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

No data available

Cross-Species Comparison

High Throughput Data

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Daniocell

Thisse Expression Data

No data available

Wild Type Expression Summary

Phenotype

All Phenotype Data: No data available
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Allele	Type	Localization	Consequence	Mutagen	Supplier
sa17141	Allele with one point mutation	Unknown	Premature Stop	ENU	Zebrafish International Resource Center (ZIRC) (order this) European Zebrafish Resource Center (EZRC) (order this)
sa31598	Allele with one point mutation	Unknown	Premature Stop	ENU	Zebrafish International Resource Center (ZIRC) (order this)

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Sequence Targeting Reagents

No data available

Human Disease

Associated With si:ch211-122f10.4 Human Ortholog

No data available

Associated With si:ch211-122f10.4 Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Active_site	IPR018202	Serine carboxypeptidase, serine active site
Active_site	IPR033124	Serine carboxypeptidases, histidine active site
Family	IPR001563	Peptidase S10, serine carboxypeptidase
Homologous_superfamily	IPR029058	Alpha/Beta hydrolase fold

Domain Details Per Protein

Protein	Additional Resources	Length	Alpha/Beta hydrolase fold	Peptidase S10, serine carboxypeptidase	Serine carboxypeptidase, serine active site	Serine carboxypeptidases, histidine active site
UniProtKB:F1QYP6	InterPro	457

Transcripts

Genome Browsers

Genome Build: GRCz11Chromosome: 7

Type	Name	Annotation Method	Length (nt)	Analysis
mRNA	si:ch211-122f10.4-201 (1) Ensembl	Ensembl	2,284 nt	Select Tool ZFIN BLAST
ncRNA	si:ch211-122f10.4-002 (1) Ensembl	Ensembl	811 nt	Select Tool ZFIN BLAST
ncRNA	si:ch211-122f10.4-003 (1) Ensembl	Ensembl	705 nt	Select Tool ZFIN BLAST

Interactions and Pathways

No data available

Antibodies

No data available

Plasmids

No data available

Constructs

No data available

Marker Relationships

No data available

Sequences

Type	Accession #	Length (nt/aa)	Analysis
RNA	RefSeq:NM_001386652 (1)	2284 nt	Select Tool ZFIN BLAST NCBI BLAST Ensembl UCSC BLAT
Genomic	GenBank:BX957362 (1)	191638 nt	Select Tool MegaBLAST Ensembl
Polypeptide	UniProtKB:F1QYP6 (1)	457 aa	Select Tool ZFIN BLAST SIB BLAST Ensembl Protein Blast

Orthology

Comparative Orthology: Alliance

No data available

Citations

Include unpublished citations

Elkon, R., Milon, B., Morrison, L., Shah, M., Vijayakumar, S., Racherla, M., Leitch, C.C., Silipino, L., Hadi, S., Weiss-Gayet, M., Barras, E., Schmid, C.D., Ait-Lounis, A., Barnes, A., Song, Y., Eisenman, D.J., Eliyahu, E., Frolenkov, G.I., Strome, S.E., Durand, B., Zaghloul, N.A., Jones, S.M., Reith, W., Hertzano, R. (2015) RFX transcription factors are essential for hearing in mice. Nature communications. 6:8549

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