ZFIN is now using GRCz12tu for Genomic Data
Gene
msh5
- ID
- ZDB-GENE-131127-632
- Name
- mutS homolog 5
- Symbol
- msh5 Nomenclature History
- Previous Names
-
- si:ch73-156o22.1 (1)
- Type
- protein_coding_gene
- Location
- Chr: 15 Mapping Details/Browsers
- Genome Assembly
- GRCz12tu
- Annotation Status
- Current
- Description
- Predicted to enable double-stranded DNA binding activity. Predicted to be involved in chiasma assembly. Predicted to act upstream of or within mismatch repair. Predicted to be active in nucleus. Human ortholog(s) of this gene implicated in lung non-small cell carcinoma; primary ovarian insufficiency 13; and spermatogenic failure 74. Orthologous to human MSH5 (mutS homolog 5).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- No data available
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| primary ovarian insufficiency 13 | Alliance | ?Premature ovarian failure 13 | 617442 |
| spermatogenic failure 74 | Alliance | Spermatogenic failure 74 | 619937 |
Domain, Family, and Site Summary
No data available
Domain Details Per Protein
| Protein | Additional Resources | Length |
|---|---|---|
| UniProtKB:A0A8M2B4N7 | InterPro | 814 |
| UniProtKB:A0AC58HDM2 | InterPro | 784 |
| UniProtKB:A0AC58HDM3 | InterPro | 805 |
| UniProtKB:A0AC58HDQ7 | InterPro | 792 |
- Genome Browsers
Interactions and Pathways
No data available
Plasmids
No data available
- Genome Browsers