Gene
adgre5a
- ID
- ZDB-GENE-130530-571
- Name
- adhesion G protein-coupled receptor E5a
- Symbol
- adgre5a Nomenclature History
- Previous Names
-
- cd97a
- si:ch211-191c10.2
- si:ch211-191c10.3
- si:ch211-241f5.3
- zmp:0000000568 (1)
- Type
- protein_coding_gene
- Location
- Chr: 3 Mapping Details/Browsers
- Description
- Is expressed in several structures, including eye; heart; integument; liver; and pleuroperitoneal region.
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 1 figure from Harty et al., 2015
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
| Allele | Type | Localization | Consequence | Mutagen | Supplier |
|---|---|---|---|---|---|
| sa11575 | Allele with one point mutation | Unknown | Premature Stop | ENU | |
| sa18127 | Allele with one point mutation | Unknown | Premature Stop | ENU | |
| sa31359 | Allele with one point mutation | Unknown | Premature Stop | ENU | |
| sa33309 | Allele with one point mutation | Unknown | Premature Stop | ENU |
1 - 4 of 4
Show
No data available
Human Disease
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Conserved_site | IPR000203 | GPS motif |
| Conserved_site | IPR018097 | EGF-like calcium-binding, conserved site |
| Domain | IPR000742 | EGF-like domain |
| Domain | IPR001881 | EGF-like calcium-binding domain |
| Domain | IPR017981 | GPCR, family 2-like, 7TM |
| Domain | IPR049883 | NOTCH1 EGF-like calcium-binding domain |
| Family | IPR000832 | GPCR, family 2, secretin-like |
| Family | IPR003056 | GPCR, family 2, ADGRE2/ADGRE5 |
| Homologous_superfamily | IPR009030 | Growth factor receptor cysteine-rich domain superfamily |
| Homologous_superfamily | IPR046338 | GAIN domain superfamily |
| PTM | IPR000152 | EGF-type aspartate/asparagine hydroxylation site |
Domain Details Per Protein
| Protein | Additional Resources | Length | EGF-like calcium-binding, conserved site | EGF-like calcium-binding domain | EGF-like domain | EGF-type aspartate/asparagine hydroxylation site | GAIN domain superfamily | GPCR, family 2, ADGRE2/ADGRE5 | GPCR, family 2-like, 7TM | GPCR, family 2, secretin-like | GPS motif | Growth factor receptor cysteine-rich domain superfamily | NOTCH1 EGF-like calcium-binding domain |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| UniProtKB:A0AB32TJY2 | InterPro | 710 | |||||||||||
| UniProtKB:A0A8M9PXQ7 | InterPro | 789 |
| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA |
adgre5a-201
(1)
|
Ensembl | 617 nt | ||
| mRNA |
si:ch211-191c10.3-201
(1)
|
Ensembl | 353 nt | ||
| mRNA |
si:ch211-241f5.3-202
(1)
|
Ensembl | 646 nt |
Interactions and Pathways
No data available
Plasmids
No data available
No data available
| Relationship | Marker Type | Marker | Accession Numbers | Citations |
|---|---|---|---|---|
| Contained in | BAC | CH211-191C10 | ZFIN Curated Data | |
| Contained in | BAC | CH211-241F5 | ZFIN Curated Data |
1 - 2 of 2
Show
| Type | Accession # | Sequence | Length (nt/aa) | Analysis |
|---|---|---|---|---|
| RNA | RefSeq:XM_068219438 (1) | 4739 nt | ||
| Genomic | RefSeq:NW_018395229 (1) | 221257 nt | ||
| Polypeptide | UniProtKB:A0A8M9PXQ7 (1) | 789 aa |
- Elkon, R., Milon, B., Morrison, L., Shah, M., Vijayakumar, S., Racherla, M., Leitch, C.C., Silipino, L., Hadi, S., Weiss-Gayet, M., Barras, E., Schmid, C.D., Ait-Lounis, A., Barnes, A., Song, Y., Eisenman, D.J., Eliyahu, E., Frolenkov, G.I., Strome, S.E., Durand, B., Zaghloul, N.A., Jones, S.M., Reith, W., Hertzano, R. (2015) RFX transcription factors are essential for hearing in mice. Nature communications. 6:8549
- Harty, B.L., Krishnan, A., Sanchez, N.E., Schiöth, H.B., Monk, K.R. (2015) Defining the gene repertoire and spatiotemporal expression profiles of adhesion G protein-coupled receptors in zebrafish. BMC Genomics. 16:62
1 - 2 of 2
Show