Gene
plcxd1.2
- ID
- ZDB-GENE-131127-421
- Name
- phospholipase C, X domain containing 1, tandem duplicate 2
- Symbol
- plcxd1.2 Nomenclature History
- Previous Names
-
- si:dkey-66a8.7 (1)
- Type
- protein_coding_gene
- Location
- Chr: 6 Mapping Details/Browsers
- Description
- Predicted to enable phosphoric diester hydrolase activity. Predicted to act upstream of or within lipid metabolic process. Orthologous to human PLCXD1 (phosphatidylinositol specific phospholipase C X domain containing 1).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- No data available
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
| Allele | Type | Localization | Consequence | Mutagen | Supplier |
|---|---|---|---|---|---|
| sa33900 | Allele with one point mutation | Unknown | Splice Site | ENU |
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No data available
Human Disease
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Domain | IPR000909 | Phosphatidylinositol-specific phospholipase C, X domain |
| Family | IPR042158 | PI-PLC X domain-containing protein 1/2/3 |
| Family | IPR051057 | Phosphoinositide phospholipase C domain-containing protein |
| Homologous_superfamily | IPR017946 | PLC-like phosphodiesterase, TIM beta/alpha-barrel domain superfamily |
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Domain Details Per Protein
| Protein | Additional Resources | Length | Phosphatidylinositol-specific phospholipase C, X domain | Phosphoinositide phospholipase C domain-containing protein | PI-PLC X domain-containing protein 1/2/3 | PLC-like phosphodiesterase, TIM beta/alpha-barrel domain superfamily |
|---|---|---|---|---|---|---|
| UniProtKB:F1QS33 | InterPro | 312 | ||||
| UniProtKB:A0A8M9Q712 | InterPro | 323 |
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| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA |
si:dkey-66a8.7-201
(1)
|
Ensembl | 1,459 nt | ||
| mRNA |
si:dkey-66a8.7-202
(1)
|
Ensembl | 228 nt |
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Interactions and Pathways
No data available
Plasmids
No data available
No data available
| Relationship | Marker Type | Marker | Accession Numbers | Citations |
|---|---|---|---|---|
| Contained in | BAC | CH211-273L18 | ZFIN Curated Data | |
| Contained in | BAC | DKEY-66A8 | ZFIN Curated Data |
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| Type | Accession # | Sequence | Length (nt/aa) | Analysis |
|---|---|---|---|---|
| RNA | RefSeq:XM_005165995 (1) | |||
| Genomic | GenBank:BX324166 (1) | 215450 nt | ||
| Polypeptide | UniProtKB:A0A8M9Q712 (1) | 323 aa |
No data available
- Zebrafish Nomenclature Committee (2025) Nomenclature Data Curation (2025). Nomenclature Committee Submission.
- Elkon, R., Milon, B., Morrison, L., Shah, M., Vijayakumar, S., Racherla, M., Leitch, C.C., Silipino, L., Hadi, S., Weiss-Gayet, M., Barras, E., Schmid, C.D., Ait-Lounis, A., Barnes, A., Song, Y., Eisenman, D.J., Eliyahu, E., Frolenkov, G.I., Strome, S.E., Durand, B., Zaghloul, N.A., Jones, S.M., Reith, W., Hertzano, R. (2015) RFX transcription factors are essential for hearing in mice. Nature communications. 6:8549
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