Gene
ncam3
- ID
- ZDB-GENE-131127-340
- Name
- neural cell adhesion molecule 3
- Symbol
- ncam3 Nomenclature History
- Previous Names
-
- si:dkey-77d17.6 (1)
- Type
- protein_coding_gene
- Location
- Chr: 16 Mapping Details/Browsers
- Description
- Predicted to enable axon guidance receptor activity. Predicted to be involved in homophilic cell adhesion via plasma membrane adhesion molecules and synapse organization. Predicted to act upstream of or within cell adhesion. Predicted to be located in membrane. Predicted to be active in axon; neuronal cell body; and plasma membrane. Is expressed in neural rod.
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 1 figure from Narboux-Neme et al., 2019
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
| Allele | Type | Localization | Consequence | Mutagen | Supplier |
|---|---|---|---|---|---|
| sa36249 | Allele with one point mutation | Unknown | Premature Stop | ENU |
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No data available
Human Disease
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Additional Resources | Length | Cell Adhesion and Cytoskeletal Organization | Fibronectin type III | Fibronectin type III superfamily | Immunoglobulin domain subtype | Immunoglobulin I-set | Immunoglobulin-like domain | Immunoglobulin-like domain superfamily | Immunoglobulin-like fold | Immunoglobulin subtype 2 | Neural cell adhesion |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| UniProtKB:A0A8M6Z1D9 | InterPro | 646 | ||||||||||
| UniProtKB:X1WF51 | InterPro | 687 | ||||||||||
| UniProtKB:A0A8M6Z223 | InterPro | 688 | ||||||||||
| UniProtKB:A0AB32T6X2 | InterPro | 645 |
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Interactions and Pathways
No data available
Plasmids
No data available
No data available
| Relationship | Marker Type | Marker | Accession Numbers | Citations |
|---|---|---|---|---|
| Contained in | BAC | CH211-240E14 | ZFIN Curated Data | |
| Contained in | BAC | DKEY-77D17 | ZFIN Curated Data |
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| Type | Accession # | Sequence | Length (nt/aa) | Analysis |
|---|---|---|---|---|
| RNA | RefSeq:XM_068214249 (1) | 4534 nt | ||
| Genomic | GenBank:AL844567 (1) | 174845 nt | ||
| Polypeptide | UniProtKB:A0A8M6Z223 (1) | 688 aa |
No data available
- Fabian, P., Tseng, K.C., Thiruppathy, M., Arata, C., Chen, H.J., Smeeton, J., Nelson, N., Crump, J.G. (2022) Lifelong single-cell profiling of cranial neural crest diversification in zebrafish. Nature communications. 13:13
- Moura-Alves, P., Puyskens, A., Stinn, A., Klemm, M., Guhlich-Bornhof, U., Dorhoi, A., Furkert, J., Kreuchwig, A., Protze, J., Lozza, L., Pei, G., Saikali, P., Perdomo, C., Mollenkopf, H.J., Hurwitz, R., Kirschhoefer, F., Brenner-Weiss, G., Weiner, J., Oschkinat, H., Kolbe, M., Krause, G., Kaufmann, S.H.E. (2019) Host monitoring of quorum sensing during Pseudomonas aeruginosa infection. Science (New York, N.Y.). 366(6472):
- Narboux-Neme, N., Ekker, M., Levi, G., Heude, E. (2019) Posterior axis formation requires Dlx5/Dlx6 expression at the neural plate border. PLoS One. 14:e0214063
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