Gene
clip3
- ID
- ZDB-GENE-131127-193
- Name
- CAP-GLY domain containing linker protein 3
- Symbol
- clip3 Nomenclature History
- Previous Names
-
- si:ch211-188j1.3
- Type
- protein_coding_gene
- Location
- Chr: 15 Mapping Details/Browsers
- Description
- Predicted to enable microtubule plus-end binding activity. Predicted to be involved in cytoplasmic microtubule organization. Predicted to be active in cell cortex; microtubule plus-end; and nucleus. Orthologous to human CLIP3 (CAP-Gly domain containing linker protein 3).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- No data available
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
| Allele | Type | Localization | Consequence | Mutagen | Supplier |
|---|---|---|---|---|---|
| sa22666 | Allele with one point mutation | Unknown | Premature Stop | ENU |
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Human Disease
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Additional Resources | Length | Ankyrin repeat | Ankyrin repeat-containing domain superfamily | CAP Gly-rich domain | CAP Gly-rich domain superfamily |
|---|---|---|---|---|---|---|
| UniProtKB:A0A0R4J8N1 | InterPro | 539 | ||||
| UniProtKB:A0A8N7T7Q1 | InterPro | 538 |
Interactions and Pathways
No data available
Plasmids
No data available
No data available
| Relationship | Marker Type | Marker | Accession Numbers | Citations |
|---|---|---|---|---|
| Contained in | BAC | CH211-188J1 | ZFIN Curated Data |
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| Type | Accession # | Sequence | Length (nt/aa) | Analysis |
|---|---|---|---|---|
| RNA | RefSeq:XM_005157740 (1) | 2204 nt | ||
| Genomic | GenBank:CR388133 (1) | 98273 nt | ||
| Polypeptide | UniProtKB:A0A0R4J8N1 (1) | 539 aa |
- Comparative Orthology
- Alliance
| Species | Symbol | Chromosome | Accession # | Evidence |
|---|---|---|---|---|
| Human | CLIP3 | 19 | Amino acid sequence comparison (1) |
- Keatinge, M., Tsarouchas, T.M., Munir, T., Porter, N.J., Larraz, J., Gianni, D., Tsai, H.H., Becker, C.G., Lyons, D.A., Becker, T. (2021) CRISPR gRNA phenotypic screening in zebrafish reveals pro-regenerative genes in spinal cord injury. PLoS Genetics. 17:e1009515
- Elkon, R., Milon, B., Morrison, L., Shah, M., Vijayakumar, S., Racherla, M., Leitch, C.C., Silipino, L., Hadi, S., Weiss-Gayet, M., Barras, E., Schmid, C.D., Ait-Lounis, A., Barnes, A., Song, Y., Eisenman, D.J., Eliyahu, E., Frolenkov, G.I., Strome, S.E., Durand, B., Zaghloul, N.A., Jones, S.M., Reith, W., Hertzano, R. (2015) RFX transcription factors are essential for hearing in mice. Nature communications. 6:8549
- Weng, J.H., Liang, M.R., Chen, C.H., Tong, S.K., Huang, T.C., Lee, S.P., Chen, Y.R., Chen, C.T., and Chung, B.C. (2013) Pregnenolone activates CLIP-170 to promote microtubule growth and cell migration. Nature Chemical Biology. 9(10):636-42
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