Gene

igfn1.4

ID

ZDB-GENE-131125-85

Name

immunoglobulin like and fibronectin type III domain containing 1, tandem duplicate 4

Symbol

igfn1.4 Nomenclature History

Previous Names

si:zfos-489f5.2
zmp:0000000879

Type

protein_coding_gene

Location

Chr: 6 Mapping Details/Browsers

Description

Orthologous to human IGFN1 (immunoglobulin like and fibronectin type III domain containing 1).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

No data available

Cross-Species Comparison

High Throughput Data

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Daniocell

Thisse Expression Data

No data available

Wild Type Expression Summary

Phenotype

All Phenotype Data: No data available
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Allele	Type	Localization	Consequence	Mutagen	Supplier
sa7047	Allele with one point mutation	Unknown	Splice Site	ENU
sa11197	Allele with one point mutation	Unknown	Premature Stop	ENU	European Zebrafish Resource Center (EZRC) (order this) Zebrafish International Resource Center (ZIRC) (order this)
sa14197	Allele with one point mutation	Unknown	Premature Stop	ENU	European Zebrafish Resource Center (EZRC) (order this) Zebrafish International Resource Center (ZIRC) (order this)
sa20805	Allele with one point mutation	Unknown	Splice Site	ENU	Zebrafish International Resource Center (ZIRC) (order this)
sa26821	Allele with one point mutation	Unknown	Splice Site	ENU	European Zebrafish Resource Center (EZRC) (order this) Zebrafish International Resource Center (ZIRC) (order this)
sa33956	Allele with one point mutation	Unknown	Splice Site	ENU	Zebrafish International Resource Center (ZIRC) (order this) European Zebrafish Resource Center (EZRC) (order this)

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Sequence Targeting Reagents

No data available

Human Disease

Associated With igfn1.4 Human Ortholog

No data available

Associated With igfn1.4 Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

No data available

Domain Details Per Protein

No data available

Transcripts

Genome Browsers

NCBI

Ensembl

ZFIN

Genome Build: GRCz11Chromosome: 6

Type	Name	Annotation Method	Has Havana Data	Length (nt)	Analysis
mRNA	igfn1.4-201 (1) Ensembl	Ensembl		4,112 nt	Select Tool ZFIN BLAST
mRNA	igfn1.4-202 (1) Ensembl	Ensembl		3,623 nt	Select Tool ZFIN BLAST

Interactions and Pathways

No data available

Antibodies

No data available

Plasmids

No data available

Constructs

No data available

Marker Relationships

Relationship	Marker Type	Marker	Accession Numbers	Citations
Contained in	Fosmid	ZFOS-489F5	CU639408	ZFIN Curated Data
Contained in	Fosmid	ZFOS-874H4	CU694440	ZFIN Curated Data

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Sequences

Type	Accession #	Length (nt/aa)	Analysis
RNA	RefSeq:XM_068221827 (1)	3711 nt	Select Tool ZFIN BLAST NCBI BLAST Ensembl UCSC BLAT
Genomic	GenBank:CU694440 (1)	43721 nt	Select Tool MegaBLAST Ensembl
Polypeptide	RefSeq:XP_021333034 (1)		Select Tool ZFIN BLAST NCBI BLAST UCSC BLAT Ensembl Protein Blast

Orthology

Comparative Orthology: Alliance

Species	Symbol	Chromosome	Accession #	Evidence
Human	IGFN1	1	Ensembl:ENSG00000163395 Gene:91156 HGNC:24607 OMIM:617309	Amino acid sequence comparison (1)
Mouse	Igfn1	1	Ensembl:ENSMUSG00000051985 Gene:226438 MGI:3045352	Amino acid sequence comparison (1)

Citations

Include unpublished citations

Zhang, P., Yao, Q., Lu, L., Li, Y., Chen, P.J., Duan, C. (2014) Hypoxia-inducible factor 3 is an oxygen-dependent transcription activator and regulates a distinct transcriptional response to hypoxia. Cell Reports. 6:1110-21

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