ZFIN is now using GRCz12tu for Genomic Data
Gene
acvr1bb
- ID
- ZDB-GENE-131120-9
- Name
- activin A receptor type 1Bb
- Symbol
- acvr1bb Nomenclature History
- Previous Names
-
- sb:eu632
- si:zfos-824d4.1 (1)
- Type
- protein_coding_gene
- Location
- Chr: 6 Mapping Details/Browsers
- Genome Assembly
- GRCz12tu
- Annotation Status
- Unknown
- Description
- Predicted to enable activin binding activity and activin receptor activity, type I. Predicted to be involved in activin receptor signaling pathway; cellular response to growth factor stimulus; and nervous system development. Predicted to be located in membrane. Predicted to be part of activin receptor complex. Predicted to be active in plasma membrane. Human ortholog(s) of this gene implicated in lung non-small cell carcinoma; lung small cell carcinoma; malignant mesothelioma; pancreatic cancer; and stomach cancer. Orthologous to human ACVR1B (activin A receptor type 1B).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 2 figures from 2 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- eu632 (1 image)
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| pancreatic carcinoma | Alliance | Pancreatic cancer, somatic | 260350 |
Domain, Family, and Site Summary
No data available
Domain Details Per Protein
No data available
- Genome Browsers
| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA |
acvr1bb-201
(1)
|
Ensembl | 1,789 nt | ||
| mRNA |
acvr1bb-202
(1)
|
Ensembl | 446 nt | ||
| mRNA |
acvr1bb-203
(1)
|
Ensembl | 1,502 nt |
Interactions and Pathways
No data available
Plasmids
No data available
- Genome Browsers