ZFIN is now using GRCz12tu for Genomic Data
Gene
ptprjb.2
- ID
- ZDB-GENE-131120-137
- Name
- protein tyrosine phosphatase receptor type Jb, tandem duplicate 2
- Symbol
- ptprjb.2 Nomenclature History
- Previous Names
-
- si:dkey-5l8.2
- Type
- protein_coding_gene
- Location
- Chr: 25 Mapping Details/Browsers
- Genome Assembly
- GRCz12tu
- Annotation Status
- Current
- Description
- Predicted to enable protein tyrosine phosphatase activity. Predicted to be involved in axon guidance and signal transduction. Human ortholog(s) of this gene implicated in colorectal cancer; lung adenocarcinoma; lung squamous cell carcinoma; and thrombocytopenia. Orthologous to human PTPRJ (protein tyrosine phosphatase receptor type J).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- No data available
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| colorectal cancer | Alliance | Colon cancer, somatic | 114500 |
| Thrombocytopenia 10 | 620484 |
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Domain | IPR000242 | Tyrosine-specific protein phosphatase, PTPase domain |
| Domain | IPR003961 | Fibronectin type III |
| Family | IPR050713 | Receptor-type Tyrosine-protein Phosphatases/Ushers |
| Homologous_superfamily | IPR013783 | Immunoglobulin-like fold |
| Homologous_superfamily | IPR029021 | Protein-tyrosine phosphatase-like |
| Homologous_superfamily | IPR036116 | Fibronectin type III superfamily |
Domain Details Per Protein
| Protein | Additional Resources | Length | Fibronectin type III | Fibronectin type III superfamily | Immunoglobulin-like fold | Protein-tyrosine phosphatase-like | Receptor-type Tyrosine-protein Phosphatases/Ushers | Tyrosine-specific protein phosphatase, PTPase domain |
|---|---|---|---|---|---|---|---|---|
| UniProtKB:A0A8M9P6I8 | InterPro | 263 | ||||||
| UniProtKB:A0AC58IYD9 | InterPro | 1522 | ||||||
| UniProtKB:A0AB32THN3 | InterPro | 1436 |
- Genome Browsers
| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA |
ptprjb.2-201
(1)
|
Ensembl | 1,042 nt |
Interactions and Pathways
No data available
Plasmids
No data available
- Genome Browsers