ptprjb.2

ID

ZDB-GENE-131120-137

Name

protein tyrosine phosphatase receptor type Jb, tandem duplicate 2

Symbol

ptprjb.2 Nomenclature History

Previous Names

si:dkey-5l8.2

Type

protein_coding_gene

Location

Chr: 25 Mapping Details/Browsers

Genome Assembly

GRCz11

Annotation Status

Unknown

Description

Predicted to enable protein tyrosine phosphatase activity. Predicted to be involved in axon guidance and signal transduction. Human ortholog(s) of this gene implicated in colorectal cancer; lung adenocarcinoma; lung squamous cell carcinoma; and thrombocytopenia. Orthologous to human PTPRJ (protein tyrosine phosphatase receptor type J).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

No data available

Cross-Species Comparison

High Throughput Data

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Thisse Expression Data

No data available

Wild Type Expression Summary

Phenotype

All Phenotype Data: No data available
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With ptprjb.2 Human Ortholog

Disease Ontology Term	Multi-Species Data	OMIM Term	OMIM Phenotype ID
colorectal cancer	Alliance	Colon cancer, somatic	114500
		Thrombocytopenia 10	620484

Associated With ptprjb.2 Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Active_site	IPR016130	Protein-tyrosine phosphatase, active site
Domain	IPR000242	Tyrosine-specific protein phosphatase, PTPase domain
Domain	IPR000387	Tyrosine-specific protein phosphatases domain
Domain	IPR003595	Protein-tyrosine phosphatase, catalytic
Family	IPR050713	Receptor-type Tyrosine-protein Phosphatases/Ushers
Homologous_superfamily	IPR029021	Protein-tyrosine phosphatase-like