si:dkey-178j11.5

ID

ZDB-GENE-131118-10

Name

si:dkey-178j11.5

Symbol

si:dkey-178j11.5 Nomenclature History

Previous Names

None

Type

protein_coding_gene

Location

Chr: 4 Mapping Details/Browsers

Genome Assembly

GRCz11

Annotation Status

Not in current annotation release

Description

Predicted to be located in cytoplasm. Human ortholog(s) of this gene implicated in CINCA Syndrome; Muckle-Wells syndrome; autosomal dominant nonsyndromic deafness 34; familial cold autoinflammatory syndrome (multiple); and urticaria. Orthologous to several human genes including NLRP12 (NLR family pyrin domain containing 12); NLRP13 (NLR family pyrin domain containing 13); and NLRP14 (NLR family pyrin domain containing 14).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

No data available

Cross-Species Comparison

High Throughput Data

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Daniocell

Thisse Expression Data

No data available

Wild Type Expression Summary

Phenotype

All Phenotype Data: No data available
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With si:dkey-178j11.5 Human Ortholog

No data available

Associated With si:dkey-178j11.5 Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Domain	IPR007111	NACHT nucleoside triphosphatase
Domain	IPR029495	NACHT-associated domain
Domain	IPR041075	NOD1/2, winged helix domain
Domain	IPR041267	NACHT, LRR and PYD domains-containing protein, helical domain HD2
Family	IPR051261	NOD-like receptor
Homologous_superfamily	IPR027417	P-loop containing nucleoside triphosphate hydrolase