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General Information
ZIRC
ZFIN ID: ZDB-GENE-131017-1
Gene Name: vinculin b
Gene Symbol: vclb
Sequence Ontology ID : SO:0000704

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(Including Attributions)
Location: Chr: 12 Mapping Details/Browsers
Nomenclature History
AUTOMATED DESCRIPTION
Predicted to have actin filament binding activity and structural molecule activity. Involved in coronary vasculature morphogenesis. Localizes to the adherens junction. Human ortholog(s) of this gene  ...
GENE EXPRESSION
All Expression Data: 2 figures from 2 publications
Wild-type Stages, Structures: Pharyngula:Prim-5 (24.0h-30.0h) to Hatching:Long-pec (48.0h-60.0h)
 
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
dhu11202 Small Deletion Exon 1 Frameshift, Premature Stop CRISPR
gd3 Small Deletion Unknown Unknown CRISPR
  • China Zebrafish Resource Center (CZRC) (order this)
  • gd4Gt Transgenic Insertion Intron 6 Unknown DNA
  • China Zebrafish Resource Center (CZRC) (order this)
  • Targeting reagents:
    DISEASE ASSOCIATED WITH vclb HUMAN ORTHOLOG
    Disease Ontology Term OMIM Term OMIM Phenotype ID
    dilated cardiomyopathy 1W Cardiomyopathy, dilated, 1W 611407
    hypertrophic cardiomyopathy 15 Cardiomyopathy, hypertrophic, 15 613255
    DISEASE ASSOCIATED WITH vclb VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process coronary vasculature morphogenesis (more)
    Cellular Component adherens junction (more)
    Molecular Function actin binding (more)
    GO Terms (all 8)
    TRANSCRIPTS No data available
    GENE PRODUCT DESCRIPTION No description available
    INTERACTIONS AND PATHWAYS
    ANTIBODIESNo data available
    PLASMIDSNo data available
    CONSTRUCTS WITH SEQUENCES FROM vclb
    MARKER RELATIONSHIPSNo data available
    SEQUENCE INFORMATION
    Type Accession # Length (bp/aa) Analysis
    RNA RefSeq:NM_001317752 (1)
    Genomic GenBank:CABZ01073962 (1) 63482bp
    Select Tool
    Polypeptide UniProtKB:A0A0S2I7K2 (1) 1066aa
    Sequence Information (all 23)
    ORTHOLOGY for vclb (Chr: 12)
    CITATIONS (10)