Gene

spink4

ID
ZDB-GENE-130821-1
Name
serine peptidase inhibitor, Kazal type 4
Symbol
spink4 Nomenclature History
Previous Names
None
Type
protein_coding_gene
Location
Chr: 1 Mapping Details/Browsers
Description
Predicted to enable serine-type endopeptidase inhibitor activity. Predicted to act upstream of or within negative regulation of peptidase activity. Predicted to be located in extracellular region. Orthologous to human SPINK4 (serine peptidase inhibitor Kazal type 4).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
No data available
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
No data available
Wild Type Expression Summary
Phenotype
All Phenotype Data
No data available
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Allele Type Localization Consequence Mutagen Supplier
zko263aAllele with one deletionUnknownUnknownCRISPR
China Zebrafish Resource Center (CZRC) (order this)
zko263bAllele with one deletionUnknownUnknownCRISPR
China Zebrafish Resource Center (CZRC) (order this)
1 - 2 of 2
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Sequence Targeting Reagents
Targeting Reagent Created Alleles Citations
CRISPR1-spink4
    		 (2)
    1 - 1 of 1
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    Human Disease
    Associated With spink4 Human Ortholog
    No data available
    Associated With spink4 Via Experimental Models
    No data available
    Gene Ontology
    Protein Domains
    Domain, Family, and Site Summary
    Type InterPro ID Name
    Domain IPR002350 Kazal domain
    Family IPR001239 Proteinase inhibitor I1, Kazal-type, metazoa
    Family IPR051597 Bifunctional protease inhibitor
    Homologous_superfamily IPR036058 Kazal domain superfamily
    1 - 4 of 4
    Domain Details Per Protein
    Protein Length Bifunctional protease inhibitor Kazal domain Kazal domain superfamily Proteinase inhibitor I1, Kazal-type, metazoa
    UniProtKB:E7FCI0
    InterPro
    		76
    1 - 1 of 1
    Transcripts
    Genome Browsers
    Genome Build: GRCz11Chromosome: 1
    Type Name Annotation Method Has Havana Data Length (nt) Analysis
    mRNA spink4-201 (1)
    Ensembl
    		Ensembl 304 nt
    ZFIN BLAST
    1 - 1 of 1
    Interactions and Pathways
    No data available
    Antibodies
    No data available
    Plasmids
    No data available
    Constructs
    No data available
    Marker Relationships
    Relationship Marker Type Marker Accession Numbers Citations
    Contained inBACCH73-321O11ZFIN Curated Data
    1 - 1 of 1
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    Sequences
    Type Accession # Sequence Length (nt/aa) Analysis
    RNARefSeq:NM_001327899 (1)383 nt
    ZFIN BLASTNCBI BLASTEnsemblUCSC BLAT
    GenomicGenBank:CU914777 (1)26587 nt
    MegaBLASTEnsembl
    PolypeptideUniProtKB:E7FCI0 (1)76 aa
    ZFIN BLASTSIB BLASTEnsembl Protein Blast
    Orthology
    Comparative Orthology
    Alliance
    Gene Tree
    Ensembl
    Species Symbol Chromosome Accession # Evidence
    HumanSPINK49
    Conserved genome location (synteny) (1)
    Amino acid sequence comparison (1)
    MouseSpink44
    Conserved genome location (synteny) (1)
    Amino acid sequence comparison (1)
    Citations
    TSV
    1 - 2 of 2
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