ZFIN is now using GRCz12tu for Genomic Data
Gene
f10l
- ID
- ZDB-GENE-130820-1
- Name
- coagulation factor X like
- Symbol
- f10l Nomenclature History
- Previous Names
- Type
- protein_coding_gene
- Location
- Unmapped
- Genome Assembly
- Unknown
- Annotation Status
- Unknown
- Description
- Predicted to enable calcium ion binding activity and serine-type endopeptidase activity. Acts upstream of or within regulation of blood coagulation. Predicted to be located in extracellular region.
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- No data available
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- 3 figures from Dhinoja et al., 2025
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Human Disease | Fish | Conditions | Citations |
|---|---|---|---|
| hemophilia B | f10lunt5/unt5 | standard conditions | Dhinoja et al., 2025 |
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Active_site | IPR018114 | Serine proteases, trypsin family, histidine active site |
| Active_site | IPR033116 | Serine proteases, trypsin family, serine active site |
| Domain | IPR000294 | Gamma-carboxyglutamic acid-rich (GLA) domain |
| Domain | IPR000742 | EGF-like domain |
| Domain | IPR001254 | Serine proteases, trypsin domain |
| Family | IPR001314 | Peptidase S1A, chymotrypsin family |
| Family | IPR012224 | Peptidase S1A, coagulation factor VII/IX/X/C/Z |
| Family | IPR050442 | Peptidase S1 family, coagulation factors |
| Homologous_superfamily | IPR009003 | Peptidase S1, PA clan |
| Homologous_superfamily | IPR017857 | Coagulation factor-like, Gla domain superfamily |
| Homologous_superfamily | IPR035972 | Gamma-carboxyglutamic acid-rich (GLA) domain superfamily |
Domain Details Per Protein
| Protein | Additional Resources | Length | Coagulation factor-like, Gla domain superfamily | EGF-like domain | Gamma-carboxyglutamic acid-rich (GLA) domain | Gamma-carboxyglutamic acid-rich (GLA) domain superfamily | Peptidase S1A, chymotrypsin family | Peptidase S1A, coagulation factor VII/IX/X/C/Z | Peptidase S1 family, coagulation factors | Peptidase S1, PA clan | Serine proteases, trypsin domain | Serine proteases, trypsin family, histidine active site | Serine proteases, trypsin family, serine active site |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| UniProtKB:A0A8M1Q266 | InterPro | 494 |
- Genome Browsers
- No data available
| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA |
zmp:0000001329-201
(1)
|
Ensembl | 1,470 nt | ||
| mRNA |
zmp:0000001329-202
(1)
|
Ensembl | 1,407 nt |
Interactions and Pathways
No data available
Plasmids
No data available
- Genome Browsers
- No data available
- Comparative Orthology
- Alliance