ZFIN is now using GRCz12tu for Genomic Data
Gene
fdxr
- ID
- ZDB-GENE-130613-2
- Name
- ferredoxin reductase
- Symbol
- fdxr Nomenclature History
- Previous Names
- None
- Type
- protein_coding_gene
- Location
- Chr: 12 Mapping Details/Browsers
- Genome Assembly
- GRCz12tu
- Annotation Status
- Current
- Description
- Predicted to enable ferredoxin-NADP+ reductase activity. Predicted to be involved in steroid biosynthetic process. Predicted to be active in mitochondrion. Human ortholog(s) of this gene implicated in auditory neuropathy and optic atrophy and multiple mitochondrial dysfunctions syndrome 9B. Orthologous to human FDXR (ferredoxin reductase).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- No data available
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| auditory neuropathy and optic atrophy | Alliance | Auditory neuropathy and optic atrophy | 617717 |
| multiple mitochondrial dysfunctions syndrome 9B | Alliance | Multiple mitochondrial dysfunctions syndrome 9B | 620887 |
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Additional Resources | Length | FAD/NAD(P)-binding domain | FAD/NAD(P)-binding domain superfamily | Ferredoxin-NADP+ reductase, adrenodoxin-type | Ferredoxin-NADP reductase-like |
|---|---|---|---|---|---|---|
| UniProtKB:E7FB58 | InterPro | 486 |
- Genome Browsers
Interactions and Pathways
No data available
Plasmids
No data available
- Genome Browsers