Gene
tap2t
- ID
- ZDB-GENE-130531-48
- Name
- transporter associated with antigen processing, subunit type t, teleost specific
- Symbol
- tap2t Nomenclature History
- Previous Names
- Type
- protein_coding_gene
- Location
- Chr: 12 Mapping Details/Browsers
- Description
- Predicted to contribute to MHC class I protein binding activity. Predicted to be involved in antigen processing and presentation of endogenous peptide antigen via MHC class I; peptide transport; and transmembrane transport. Predicted to localize to MHC class I peptide loading complex. Human ortholog(s) of this gene implicated in several diseases, including MHC class I deficiency; autoimmune hypersensitivity disease (multiple); bone inflammation disease (multiple); cervical cancer (multiple); and dengue hemorrhagic fever. Orthologous to human TAP2 (transporter 2, ATP binding cassette subfamily B member).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- No data available
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Conserved_site | IPR017871 | ABC transporter-like, conserved site |
| Domain | IPR003439 | ABC transporter-like, ATP-binding domain |
| Domain | IPR003593 | AAA+ ATPase domain |
| Domain | IPR011527 | ABC transporter type 1, transmembrane domain |
| Family | IPR039421 | Type 1 protein exporter |
| Homologous_superfamily | IPR027417 | P-loop containing nucleoside triphosphate hydrolase |
| Homologous_superfamily | IPR036640 | ABC transporter type 1, transmembrane domain superfamily |
Domain Details Per Protein
| Protein | Length | AAA+ ATPase domain | ABC transporter-like, ATP-binding domain | ABC transporter-like, conserved site | ABC transporter type 1, transmembrane domain | ABC transporter type 1, transmembrane domain superfamily | P-loop containing nucleoside triphosphate hydrolase | Type 1 protein exporter |
|---|---|---|---|---|---|---|---|---|
|
UniProtKB:E7F2I0
|
728 | |||||||
|
UniProtKB:A0A8M9PTJ0
|
400 |
Interactions and Pathways
No data available
Plasmids
No data available
- Comparative Orthology
- Alliance