cita

ID

ZDB-GENE-130530-981

Name

citron rho-interacting serine/threonine kinase a

Symbol

cita Nomenclature History

Previous Names

cit
zmp:0000000978 (1)

Type

protein_coding_gene

Location

Chr: 5 Mapping Details/Browsers

Genome Assembly

GRCz12tu

Annotation Status

Current

Description

Predicted to enable ATP binding activity; metal ion binding activity; and protein kinase activity. Predicted to be involved in regulation of actin cytoskeleton organization. Predicted to act upstream of or within protein phosphorylation. Human ortholog(s) of this gene implicated in primary autosomal recessive microcephaly 17 and primary microcephaly. Orthologous to human CIT (citron rho-interacting serine/threonine kinase).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

No data available

Cross-Species Comparison

High Throughput Data

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Daniocell

Thisse Expression Data

No data available

Wild Type Expression Summary

Phenotype

All Phenotype Data: 2 figures from Iegiani et al., 2025
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With cita Human Ortholog

Disease Ontology Term	Multi-Species Data	OMIM Term	OMIM Phenotype ID
primary autosomal recessive microcephaly 17	Alliance	Microcephaly 17, primary, autosomal recessive	617090

Associated With cita Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

No data available

Domain Details Per Protein

Protein	Additional Resources	Length
UniProtKB:E7FGD8	InterPro	1989
UniProtKB:A0A8M9QF24	InterPro	2344
UniProtKB:A0A8M9PZB2	InterPro	2358
UniProtKB:A0A8M9Q5W0	InterPro	2350
UniProtKB:A0A8M9QA07	InterPro	2336
UniProtKB:A0AB32TPP6	InterPro	1908
UniProtKB:A0AC58JMZ6	InterPro	2119
UniProtKB:A0AC58JN00	InterPro	2119
UniProtKB:A0AC58JN01	InterPro	2119
UniProtKB:A0AC58JN03	InterPro	2118
UniProtKB:A0AC58JN04	InterPro	2105
UniProtKB:A0AC58JN06	InterPro	2110
UniProtKB:A0AC58JN07	InterPro	2104
UniProtKB:A0AC58JN08	InterPro	1997
UniProtKB:A0AC58JN09	InterPro	2096
UniProtKB:A0AC58JN10	InterPro	2097
UniProtKB:A0AC58JN11	InterPro	1989
UniProtKB:A0AC58JN12	InterPro	2097
UniProtKB:A0AC58JN13	InterPro	2003
UniProtKB:A0AC58JN14	InterPro	2111
UniProtKB:A0AC58JN17	InterPro	1989
UniProtKB:A0AC58JN36	InterPro	1989