Gene
zmp:0000000936
- ID
- ZDB-GENE-130530-939
- Name
- zmp:0000000936
- Symbol
- zmp:0000000936 Nomenclature History
- Previous Names
- None
- Type
- protein_coding_gene
- Location
- Chr: 9 Mapping Details/Browsers
- Description
- Predicted to enable hydrolase activity and interleukin-1 receptor activity. Acts upstream of or within regulation of inflammatory response and regulation of neutrophil migration. Predicted to be located in membrane. Predicted to be active in cell surface and plasma membrane. Human ortholog(s) of this gene implicated in chronic recurrent multifocal osteomyelitis; systemic scleroderma; and type 1 diabetes mellitus. Orthologous to several human genes including IL1R1 (interleukin 1 receptor type 1).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 1 figure from Sebo et al., 2022
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Domain | IPR000157 | Toll/interleukin-1 receptor homology (TIR) domain |
| Domain | IPR003599 | Immunoglobulin domain subtype |
| Domain | IPR007110 | Immunoglobulin-like domain |
| Family | IPR004074 | Interleukin-1 receptor type I/II |
| Family | IPR015621 | Interleukin-1 receptor family |
| Homologous_superfamily | IPR013783 | Immunoglobulin-like fold |
| Homologous_superfamily | IPR035897 | Toll/interleukin-1 receptor homology (TIR) domain superfamily |
| Homologous_superfamily | IPR036179 | Immunoglobulin-like domain superfamily |
Domain Details Per Protein
| Protein | Length | Immunoglobulin domain subtype | Immunoglobulin-like domain | Immunoglobulin-like domain superfamily | Immunoglobulin-like fold | Interleukin-1 receptor family | Interleukin-1 receptor type I/II | Toll/interleukin-1 receptor homology (TIR) domain | Toll/interleukin-1 receptor homology (TIR) domain superfamily |
|---|---|---|---|---|---|---|---|---|---|
|
UniProtKB:E7F5V6
|
580 |
- Genome Browsers
| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA |
zmp:0000000936-201
(1)
|
Ensembl | 1,989 nt |
Interactions and Pathways
No data available
Plasmids
No data available
- Comparative Orthology
- Alliance