Gene

sorcs2

ID

ZDB-GENE-130530-825

Name

sortilin-related VPS10 domain containing receptor 2

Symbol

sorcs2 Nomenclature History

Previous Names

zmp:0000000822 (1)

Type

protein_coding_gene

Location

Chr: 7 Mapping Details/Browsers

Description

Predicted to localize to integral component of membrane. Orthologous to human SORCS2 (sortilin related VPS10 domain containing receptor 2).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

No data available

Cross-Species Comparison

High Throughput Data

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Daniocell

Thisse Expression Data

No data available

Wild Type Expression Summary

Phenotype

All Phenotype Data: No data available
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With sorcs2 Human Ortholog

No data available

Associated With sorcs2 Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Domain	IPR000601	PKD domain
Domain	IPR006581	VPS10
Domain	IPR031777	Sortilin, C-terminal
Domain	IPR031778	Sortilin, N-terminal
Family	IPR050310	VPS10-related sortilin family receptors
Homologous_superfamily	IPR013783	Immunoglobulin-like fold
Homologous_superfamily	IPR015943	WD40/YVTN repeat-like-containing domain superfamily
Homologous_superfamily	IPR035986	PKD domain superfamily

Domain Details Per Protein

Protein	Length	Immunoglobulin-like fold	PKD domain	PKD domain superfamily	Sortilin, C-terminal	Sortilin, N-terminal	VPS10	VPS10-related sortilin family receptors	WD40/YVTN repeat-like-containing domain superfamily
UniProtKB:A0A8M3B1D9 InterPro	1158
UniProtKB:A0A8M9Q2P2 InterPro	1142
UniProtKB:A0A8M9Q8U3 InterPro	1071
UniProtKB:A0A8M9PQ08 InterPro	1167
UniProtKB:E7FD83 InterPro	1133

Transcripts

Genome Browsers

NCBI

Ensembl

ZFIN

Type	Name	Annotation Method	Has Havana Data	Length (nt)	Analysis
mRNA	sorcs2-201 (1) Ensembl	Ensembl		7,850 nt	Select Tool ZFIN BLAST
mRNA	sorcs2-202 (1) Ensembl	Ensembl		3,279 nt	Select Tool ZFIN BLAST

Interactions and Pathways

No data available

Antibodies

No data available

Plasmids

No data available

Constructs

Marker Relationships

Sequences

Orthology

Comparative Orthology: Alliance

Citations