Gene
znf335
- ID
- ZDB-GENE-130530-814
- Name
- zinc finger protein 335
- Symbol
- znf335 Nomenclature History
- Previous Names
-
- si:ch211-269m15.3
- zmp:0000000811 (1)
- Type
- protein_coding_gene
- Location
- Chr: 8 Mapping Details/Browsers
- Description
- Predicted to enable RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Predicted to be involved in brain development; positive regulation of neurogenesis; and positive regulation of transcription by RNA polymerase II. Predicted to be active in nucleus. Human ortholog(s) of this gene implicated in primary autosomal recessive microcephaly 10. Orthologous to human ZNF335 (zinc finger protein 335).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- No data available
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| primary autosomal recessive microcephaly 10 | Alliance | Microcephaly 10, primary, autosomal recessive | 615095 |
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Additional Resources | Length | AT hook, DNA-binding motif | Zinc finger and ubiquitin peptidase domain-containing protein | Zinc finger C2H2 superfamily | Zinc finger C2H2-type |
|---|---|---|---|---|---|---|
| UniProtKB:A0A8M6Z7U1 | InterPro | 1527 | ||||
| UniProtKB:A0A8M2BEI4 | InterPro | 1534 |
| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| aberrant processed transcript |
znf335-202
(1)
|
Ensembl | 667 nt | ||
| mRNA |
znf335-204
(1)
|
Ensembl | 6,162 nt | ||
| mRNA |
znf335-205
(1)
|
Ensembl | 4,546 nt | ||
| mRNA |
znf335-206
(1)
|
Ensembl | 4,204 nt | ||
| mRNA |
znf335-207
(1)
|
Ensembl | 4,576 nt | ||
| mRNA |
znf335-208
(1)
|
Ensembl | 4,205 nt | ||
| mRNA |
znf335-209
(1)
|
Ensembl | 3,682 nt | ||
| mRNA |
znf335-210
(1)
|
Ensembl | 4,368 nt | ||
| mRNA |
znf335-211
(1)
|
Ensembl | 9,182 nt | ||
| mRNA |
znf335-212
(1)
|
Ensembl | 4,416 nt | ||
| mRNA |
znf335-213
(1)
|
Ensembl | 5,421 nt | ||
| ncRNA |
si:ch211-269m15.3-003
(1)
|
Ensembl | 610 nt | ||
| ncRNA |
si:ch211-269m15.3-004
(1)
|
Ensembl | 730 nt |
Interactions and Pathways
No data available
Plasmids
No data available
- Comparative Orthology
- Alliance