Gene

grin3a

ID

ZDB-GENE-130530-780

Name

glutamate receptor, ionotropic, N-methyl-D-aspartate 3A

Symbol

grin3a Nomenclature History

Previous Names

zmp:0000000777 (1)

Type

protein_coding_gene

Location

Chr: 10 Mapping Details/Browsers

Description

Predicted to enable glutamate receptor activity and transmitter-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential. Predicted to contribute to NMDA glutamate receptor activity. Predicted to be involved in glutamatergic synaptic transmission; ionotropic glutamate receptor signaling pathway; and modulation of chemical synaptic transmission. Predicted to act upstream of or within monoatomic ion transmembrane transport. Predicted to be located in postsynaptic membrane. Predicted to be active in postsynaptic density membrane. Orthologous to human GRIN3A (glutamate ionotropic receptor NMDA type subunit 3A).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

1 figure from Zielonka et al., 2018

Cross-Species Comparison

High Throughput Data

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Daniocell

Thisse Expression Data

No data available

Wild Type Expression Summary

Phenotype

All Phenotype Data: No data available
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With grin3a Human Ortholog

No data available

Associated With grin3a Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Domain	IPR001320	Ionotropic glutamate receptor, C-terminal
Domain	IPR001828	Receptor, ligand binding region
Domain	IPR019594	Ionotropic glutamate receptor, L-glutamate and glycine-binding domain
Family	IPR001508	Ionotropic glutamate receptor, metazoa
Family	IPR015683	Ionotropic glutamate receptor
Homologous_superfamily	IPR028082	Periplasmic binding protein-like I

Domain Details Per Protein

Protein	Length	Ionotropic glutamate receptor	Ionotropic glutamate receptor, C-terminal	Ionotropic glutamate receptor, L-glutamate and glycine-binding domain	Ionotropic glutamate receptor, metazoa	Periplasmic binding protein-like I	Receptor, ligand binding region
UniProtKB:E7F902 InterPro	1114
UniProtKB:A0A8M3AWH5 InterPro	1111

Transcripts

Genome Browsers

NCBI

No data available

Interactions and Pathways

No data available

Antibodies

No data available

Plasmids

No data available

Constructs

Marker Relationships

Sequences

Orthology

Comparative Orthology: Alliance

Citations