Gene
gucy1b2
- ID
- ZDB-GENE-130530-664
- Name
- guanylate cyclase 1, soluble, beta 2
- Symbol
- gucy1b2 Nomenclature History
- Previous Names
-
- zmp:0000000661 (1)
- Type
- protein_coding_gene
- Location
- Chr: 11 Mapping Details/Browsers
- Description
- Predicted to enable GTP binding activity; guanylate cyclase activity; and heme binding activity. Predicted to act upstream of or within cGMP biosynthetic process and intracellular signal transduction. Predicted to be located in cytoplasm. Is expressed in olfactory epithelium and olfactory receptor cell. Orthologous to human GUCY1B2 (guanylate cyclase 1 soluble subunit beta 2 (pseudogene)).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 1 figure from Saraiva et al., 2015
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Conserved_site | IPR018297 | Adenylyl cyclase class-4/guanylyl cyclase, conserved site |
| Domain | IPR001054 | Adenylyl cyclase class-3/4/guanylyl cyclase |
| Domain | IPR011644 | Heme NO-binding |
| Domain | IPR011645 | Haem NO binding associated |
| Homologous_superfamily | IPR024096 | NO signalling/Golgi transport ligand-binding domain superfamily |
| Homologous_superfamily | IPR029787 | Nucleotide cyclase |
| Homologous_superfamily | IPR038158 | H-NOX domain superfamily |
| Homologous_superfamily | IPR042463 | Haem NO binding associated domain superfamily |
Domain Details Per Protein
| Protein | Length | Adenylyl cyclase class-3/4/guanylyl cyclase | Adenylyl cyclase class-4/guanylyl cyclase, conserved site | Haem NO binding associated | Haem NO binding associated domain superfamily | Heme NO-binding | H-NOX domain superfamily | NO signalling/Golgi transport ligand-binding domain superfamily | Nucleotide cyclase |
|---|---|---|---|---|---|---|---|---|---|
|
UniProtKB:E7F6T1
|
757 |
| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA |
gucy1b2-201
(1)
|
Ensembl | 2,343 nt |
Interactions and Pathways
No data available
Plasmids
No data available
- Comparative Orthology
- Alliance