Gene
amfrb
- ID
- ZDB-GENE-130530-643
- Name
- autocrine motility factor receptor b
- Symbol
- amfrb Nomenclature History
- Previous Names
-
- zmp:0000000640 (1)
- Type
- protein_coding_gene
- Location
- Chr: 7 Mapping Details/Browsers
- Description
- Predicted to enable ubiquitin protein ligase activity. Predicted to be involved in endoplasmic reticulum unfolded protein response; protein K48-linked ubiquitination; and ubiquitin-dependent protein catabolic process. Predicted to be located in membrane. Predicted to be part of ubiquitin ligase complex. Predicted to be active in cytosol and endoplasmic reticulum. Orthologous to human AMFR (autocrine motility factor receptor).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- No data available
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| hereditary spastic paraplegia 89 | Alliance | Spastic paraplegia 89, autosomal recessive | 620379 |
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Length | Zinc finger, RING/FYVE/PHD-type | Zinc finger, RING-type |
|---|---|---|---|
|
UniProtKB:A0A2R8QB56
|
401 | ||
|
UniProtKB:A0A8M9Q2M5
|
307 | ||
|
UniProtKB:A0A1D5NS78
|
459 |
Interactions and Pathways
No data available
Plasmids
No data available