tsg101b

ID

ZDB-GENE-130530-542

Name

tumor susceptibility 101b

Symbol

tsg101b Nomenclature History

Previous Names

zmp:0000000539 (1)

Type

protein_coding_gene

Location

Chr: 7 Mapping Details/Browsers

Genome Assembly

GRCz12tu

Annotation Status

Current

Description

Predicted to enable ubiquitin binding activity. Predicted to be involved in endosome to lysosome transport. Predicted to be located in endosome and nucleus. Predicted to be part of ESCRT I complex. Human ortholog(s) of this gene implicated in breast cancer; breast carcinoma; cervix carcinoma; endometrial adenocarcinoma; and prostate cancer. Orthologous to human TSG101 (tumor susceptibility 101).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

No data available

Cross-Species Comparison

High Throughput Data

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Daniocell

Thisse Expression Data

No data available

Wild Type Expression Summary

Phenotype

All Phenotype Data: No data available
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With tsg101b Human Ortholog

No data available

Associated With tsg101b Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Domain	IPR008883	Ubiquitin E2 variant, N-terminal
Domain	IPR017916	Steadiness box (SB) domain
Family	IPR052070	ESCRT-I complex UEV domain-containing protein
Homologous_superfamily	IPR016135	Ubiquitin-conjugating enzyme/RWD-like
Homologous_superfamily	IPR037202	ESCRT assembly domain