Gene
drd5a
- ID
- ZDB-GENE-130522-2
- Name
- dopamine receptor D5a
- Symbol
- drd5a Nomenclature History
- Previous Names
-
- D1Ba (1)
- Type
- protein_coding_gene
- Location
- Chr: 14 Mapping Details/Browsers
- Description
- Predicted to enable alpha2-adrenergic receptor activity and dopamine neurotransmitter receptor activity. Predicted to be involved in adenylate cyclase-inhibiting adrenergic receptor signaling pathway. Predicted to act upstream of or within adenylate cyclase-activating G protein-coupled receptor signaling pathway. Predicted to be located in plasma membrane. Human ortholog(s) of this gene implicated in attention deficit hyperactivity disorder and blepharospasm. Orthologous to human DRD5 (dopamine receptor D5).
- Genome Resources
-
- Alliance (1)
- Gene:100536970 (1)
- Note
- None
- Comparative Information
-
- All Expression Data
- 1 figure from Leggieri et al., 2022
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| attention deficit hyperactivity disorder | Alliance | {Attention deficit-hyperactivity disorder, susceptibility to} | 143465 |
| {Blepharospasm, primary benign} | 606798 |
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Length | Dopamine D5 receptor | Dopamine receptor family | GPCR, rhodopsin-like, 7TM | G protein-coupled receptor, rhodopsin-like |
|---|---|---|---|---|---|
|
UniProtKB:A0A8M1RJ11
|
281 |
- Genome Browsers
Interactions and Pathways
No data available
Plasmids
No data available
- Comparative Orthology
- Alliance