Gene

unc93b1

ID
ZDB-GENE-130424-1
Name
unc-93 homolog B1, TLR signaling regulator
Symbol
unc93b1 Nomenclature History
Previous Names
None
Type
protein_coding_gene
Location
Chr: 1 Mapping Details/Browsers
Description
Predicted to have Toll-like receptor binding activity. Involved in regulation of toll-like receptor signaling pathway. Predicted to localize to endosome and lysosome. Is expressed in heart; liver; muscle; and pleuroperitoneal region. Human ortholog(s) of this gene implicated in brain disease. Orthologous to human UNC93B1 (unc-93 homolog B1, TLR signaling regulator).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
1 figure from Yeh et al., 2013
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
No data available
Wild Type Expression Summary
Phenotype
All Phenotype Data
No data available
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With unc93b1 Human Ortholog
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
{Encephalopathy, acute, infection-induced (herpes-specific), susceptibility to, 1} 610551
Associated With unc93b1 Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Family IPR010291 Ion channel regulatory protein, UNC-93
Family IPR043268 Protein unc-93 homolog B1
Homologous_superfamily IPR036259 MFS transporter superfamily
Domain Details Per Protein
Protein Length Ion channel regulatory protein, UNC-93 MFS transporter superfamily Protein unc-93 homolog B1
UniProtKB:F1QYA8 623
Transcripts
Genome Browsers
Type Name Annotation Method Length (nt) Analysis
mRNA unc93b1-201 (1) Ensembl 2375 nt
mRNA unc93b1-202 (1) Havana 2489 nt
mRNA unc93b1-203 (1) Ensembl 2453 nt
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations