Gene

fyco1b

ID

ZDB-GENE-130326-1

Name

FYVE and coiled-coil domain autophagy adaptor 1b

Symbol

fyco1b Nomenclature History

Previous Names

zmp:0000000838 (1)

Type

protein_coding_gene

Location

Chr: 2 Mapping Details/Browsers

Description

Predicted to have metal ion binding activity. Predicted to be involved in plus-end-directed vesicle transport along microtubule and positive regulation of autophagosome maturation. Human ortholog(s) of this gene implicated in cataract 18. Orthologous to human FYCO1 (FYVE and coiled-coil domain autophagy adaptor 1).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

No data available

Cross-Species Comparison

High Throughput Data

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Daniocell

Thisse Expression Data

No data available

Wild Type Expression Summary

Phenotype

All Phenotype Data: No data available
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With fyco1b Human Ortholog

Disease Ontology Term	Multi-Species Data	OMIM Term	OMIM Phenotype ID
cataract 18	Alliance	Cataract 18, autosomal recessive	610019

Associated With fyco1b Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Domain	IPR000306	FYVE zinc finger
Domain	IPR004012	RUN domain
Domain	IPR009038	GOLD domain
Domain	IPR017455	Zinc finger, FYVE-related
Domain	IPR047336	FYCO1, RUN domain
Domain	IPR047337	FYCO1, FYVE domain
Homologous_superfamily	IPR011011	Zinc finger, FYVE/PHD-type
Homologous_superfamily	IPR013083	Zinc finger, RING/FYVE/PHD-type
Homologous_superfamily	IPR036598	GOLD domain superfamily
Homologous_superfamily	IPR037213	RUN domain superfamily

Domain Details Per Protein

Protein	Length	FYCO1, FYVE domain	FYCO1, RUN domain	FYVE zinc finger	GOLD domain	GOLD domain superfamily	RUN domain	RUN domain superfamily	Zinc finger, FYVE/PHD-type	Zinc finger, FYVE-related	Zinc finger, RING/FYVE/PHD-type
UniProtKB:F1RDW0 InterPro
UniProtKB:A0A8M6YUP3 InterPro	1298
UniProtKB:A0A8M1RLQ4 InterPro	1346

Transcripts

Genome Browsers

NCBI

Type	Name	Annotation Method	Has Havana Data	Length (nt)	Analysis
mRNA	fyco1-201 (1) Ensembl	Ensembl		3,663 nt	Select Tool ZFIN BLAST
mRNA	fyco1-202 (1) Ensembl	Ensembl		3,492 nt	Select Tool ZFIN BLAST

Interactions and Pathways

No data available

Antibodies

No data available

Plasmids

No data available

Constructs

Marker Relationships

Sequences

Orthology

Comparative Orthology: Alliance

Citations