Gene
cers3a
- ID
- ZDB-GENE-130320-1
- Name
- ceramide synthase 3a
- Symbol
- cers3a Nomenclature History
- Previous Names
- None
- Type
- protein_coding_gene
- Location
- Chr: 7 Mapping Details/Browsers
- Description
- Predicted to have DNA binding activity and transferase activity. Predicted to be involved in lipid metabolic process. Predicted to localize to several cellular components, including endoplasmic reticulum; endoplasmic reticulum membrane; and integral component of membrane. Is expressed in several structures, including digestive system; immature eye; intermediate cell mass of mesoderm; myotome; and pectoral fin. Human ortholog(s) of this gene implicated in autosomal recessive congenital ichthyosis 9. Orthologous to human CERS3 (ceramide synthase 3).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 2 figures from Brondolin et al., 2013
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| autosomal recessive congenital ichthyosis 9 | Alliance | Ichthyosis, congenital, autosomal recessive 9 | 615023 |
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Length | Homedomain-like superfamily | Homeodomain | Sphingosine N-acyltransferase Lag1/Lac1-like | TRAM/LAG1/CLN8 homology domain |
|---|---|---|---|---|---|
|
UniProtKB:A0A8M9Q8A3
|
208 | ||||
|
UniProtKB:A0A8M9Q249
|
293 | ||||
|
UniProtKB:A0A140LFW4
|
380 |
| Type | Name | Annotation Method | Length (nt) | Analysis |
|---|---|---|---|---|
| mRNA |
cers3a-201
(1)
|
Ensembl | 1053 nt | |
| mRNA |
cers3a-202
(1)
|
Havana | 4937 nt | |
| mRNA |
cers3a-203
(1)
|
Ensembl | 1032 nt |
Interactions and Pathways
No data available
Plasmids
No data available
- Comparative Orthology
- Alliance