ZFIN is now using GRCz12tu for Genomic Data
Gene
sphk1
- ID
- ZDB-GENE-130312-3
- Name
- sphingosine kinase 1
- Symbol
- sphk1 Nomenclature History
- Previous Names
- None
- Type
- protein_coding_gene
- Location
- Ambiguous Mapping Details/Browsers
- Genome Assembly
- GRCz12tu
- Annotation Status
- Current
- Description
- Predicted to enable sphingosine kinase activity. Acts upstream of or within blood vessel endothelial cell migration. Predicted to be located in endomembrane system. Predicted to be active in cytoplasm and plasma membrane.
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 4 figures from 4 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Domain | IPR001206 | Diacylglycerol kinase, catalytic domain |
| Domain | IPR045540 | YegS/DAGK, C-terminal domain |
| Family | IPR050187 | Lipid Phosphate Formation and Regulation |
| Homologous_superfamily | IPR016064 | NAD kinase/diacylglycerol kinase-like domain superfamily |
| Homologous_superfamily | IPR017438 | Inorganic polyphosphate/ATP-NAD kinase, N-terminal |
Domain Details Per Protein
| Protein | Additional Resources | Length | Diacylglycerol kinase, catalytic domain | Inorganic polyphosphate/ATP-NAD kinase, N-terminal | Lipid Phosphate Formation and Regulation | NAD kinase/diacylglycerol kinase-like domain superfamily | YegS/DAGK, C-terminal domain |
|---|---|---|---|---|---|---|---|
| UniProtKB:A0A8M1RS71 | InterPro | 493 |
- Genome Browsers
Interactions and Pathways
No data available
Plasmids
No data available
- Genome Browsers