Gene
fmnl1b
- ID
- ZDB-GENE-130306-1
- Name
- formin-like 1b
- Symbol
- fmnl1b Nomenclature History
- Previous Names
-
- zmp:0000001155
- Type
- protein_coding_gene
- Location
- Chr: 24 Mapping Details/Browsers
- Description
- Predicted to enable actin filament binding activity. Predicted to be involved in cell migration; cortical actin cytoskeleton organization; and regulation of cell shape. Predicted to act upstream of or within actin cytoskeleton organization and regulation of cell morphogenesis. Predicted to be active in cytosol. Is expressed in several structures, including myotome; nervous system; notochord; optic cup; and trunk. Orthologous to human FMNL1 (formin like 1).
- Genome Resources
-
- Alliance (1)
- Gene:100536330 (1)
- Note
- None
- Comparative Information
-
- All Expression Data
- 7 figures from 2 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Domain | IPR010472 | Formin, FH3 domain |
| Domain | IPR010473 | Formin, GTPase-binding domain |
| Domain | IPR014767 | Diaphanous autoregulatory (DAD) domain |
| Domain | IPR014768 | Rho GTPase-binding/formin homology 3 (GBD/FH3) domain |
| Domain | IPR015425 | Formin, FH2 domain |
| Family | IPR043592 | Formin-like protein, animal |
| Homologous_superfamily | IPR011989 | Armadillo-like helical |
| Homologous_superfamily | IPR016024 | Armadillo-type fold |
| Homologous_superfamily | IPR042201 | Formin, FH2 domain superfamily |
Domain Details Per Protein
| Protein | Additional Resources | Length | Armadillo-like helical | Armadillo-type fold | Diaphanous autoregulatory (DAD) domain | Formin, FH2 domain | Formin, FH2 domain superfamily | Formin, FH3 domain | Formin, GTPase-binding domain | Formin-like protein, animal | Rho GTPase-binding/formin homology 3 (GBD/FH3) domain |
|---|---|---|---|---|---|---|---|---|---|---|---|
| UniProtKB:A0A8M3APF0 | InterPro | 1026 |
- Genome Browsers
Interactions and Pathways
No data available
Plasmids
No data available
- Comparative Orthology
- Alliance