Gene
nags
- ID
- ZDB-GENE-121219-2
- Name
- N-acetylglutamate synthase
- Symbol
- nags Nomenclature History
- Previous Names
- None
- Type
- protein_coding_gene
- Location
- Chr: 3 Mapping Details/Browsers
- Description
- Enables L-glutamate N-acetyltransferase activity and arginine binding activity. Predicted to be involved in L-arginine biosynthetic process and glutamate metabolic process. Predicted to be active in mitochondrial matrix. Human ortholog(s) of this gene implicated in N-acetylglutamate synthase deficiency and amino acid metabolic disorder. Orthologous to human NAGS (N-acetylglutamate synthase).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 1 figure from Caldovic et al., 2014
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| N-acetylglutamate synthase deficiency | Alliance | N-acetylglutamate synthase deficiency | 237310 |
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Additional Resources | Length | Acetylglutamate kinase-like superfamily | Acyl-CoA N-acyltransferase | N-acetylglutamate synthase, animal | Vertebrate-like NAGS Gcn5-related N-acetyltransferase (GNAT) domain |
|---|---|---|---|---|---|---|
| UniProtKB:E7FCP8 | InterPro | 527 | ||||
| UniProtKB:A0A8M9PWK2 | InterPro | 526 | ||||
| UniProtKB:A0A8M9PJE2 | InterPro | 526 | ||||
| UniProtKB:A0A8M9P8E6 | InterPro | 527 | ||||
| UniProtKB:A0AB13ABJ3 | InterPro | 526 |
Interactions and Pathways
No data available
Plasmids
No data available