Gene
si:dkey-269i1.4
- ID
- ZDB-GENE-121214-37
- Name
- si:dkey-269i1.4
- Symbol
- si:dkey-269i1.4 Nomenclature History
- Previous Names
-
- ctsl (1)
- Type
- protein_coding_gene
- Location
- Chr: 12 Mapping Details/Browsers
- Description
- Predicted to enable cysteine-type peptidase activity. Predicted to act upstream of or within proteolysis. Predicted to be located in lysosome.
- Genome Resources
- Note
-
This sequence is in a cluster of genes on chromosome 12 that may or may not be tandem duplicates of ctsl.
- Comparative Information
-
- All Expression Data
- No data available
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
| Allele | Type | Localization | Consequence | Mutagen | Supplier |
|---|---|---|---|---|---|
| sa30959 | Allele with one point mutation | Unknown | Premature Stop | ENU | |
| sa31870 | Allele with one point mutation | Unknown | Premature Stop | ENU | |
| sa35247 | Allele with one point mutation | Unknown | Premature Stop | ENU | |
| sa42000 | Allele with one point mutation | Unknown | Premature Stop | ENU |
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No data available
Human Disease
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Active_site | IPR000169 | Cysteine peptidase, cysteine active site |
| Active_site | IPR025660 | Cysteine peptidase, histidine active site |
| Active_site | IPR025661 | Cysteine peptidase, asparagine active site |
| Domain | IPR000668 | Peptidase C1A, papain C-terminal |
| Domain | IPR013201 | Cathepsin propeptide inhibitor domain (I29) |
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Domain Details Per Protein
| Protein | Additional Resources | Length | Cathepsin propeptide inhibitor domain (I29) | Cysteine peptidase, asparagine active site | Cysteine peptidase, cysteine active site | Cysteine peptidase, histidine active site | Papain-like cysteine endopeptidase | Papain-like cysteine peptidase superfamily | Peptidase C1A | Peptidase C1A, papain C-terminal |
|---|---|---|---|---|---|---|---|---|---|---|
| UniProtKB:A8E587 | InterPro | 336 | ||||||||
| UniProtKB:A0A8M1NEU9 | InterPro | 336 |
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| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA |
si:dkey-269i1.4-201
(1)
|
Ensembl | 1,275 nt |
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Interactions and Pathways
No data available
Plasmids
No data available
No data available
| Relationship | Marker Type | Marker | Accession Numbers | Citations |
|---|---|---|---|---|
| Contained in | BAC | DKEY-269I1 | ZFIN Curated Data |
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| Type | Accession # | Sequence | Length (nt/aa) | Analysis |
|---|---|---|---|---|
| RNA | RefSeq:NM_001105680 (1) | |||
| Genomic | GenBank:BX322603 (1) | 191741 nt | ||
| Polypeptide | UniProtKB:A0A8M1NEU9 (1) | 336 aa |
- Comparative Orthology
- Alliance
No data available