Gene
adgre5b.3
- ID
- ZDB-GENE-121214-275
- Name
- adhesion G protein-coupled receptor E5b, duplicate 3
- Symbol
- adgre5b.3 Nomenclature History
- Previous Names
-
- Cd97d (1)
- si:ch73-221f6.7
- Type
- protein_coding_gene
- Location
- Chr: 1 Mapping Details/Browsers
- Description
- Predicted to enable G protein-coupled receptor activity. Predicted to be involved in G protein-coupled receptor signaling pathway. Predicted to act upstream of or within cell adhesion and cell surface receptor signaling pathway. Predicted to be located in membrane. Predicted to be active in plasma membrane. Is expressed in several structures, including eye; heart; integument; liver; and pleuroperitoneal region. Human ortholog(s) of this gene implicated in vibratory urticaria. Orthologous to several human genes including ADGRE5 (adhesion G protein-coupled receptor E5).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 1 figure from Harty et al., 2015
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Conserved_site | IPR000203 | GPS motif |
| Conserved_site | IPR018097 | EGF-like calcium-binding, conserved site |
| Domain | IPR000742 | EGF-like domain |
| Domain | IPR001881 | EGF-like calcium-binding domain |
| Domain | IPR017981 | GPCR, family 2-like, 7TM |
| Domain | IPR049883 | NOTCH1 EGF-like calcium-binding domain |
| Family | IPR000832 | GPCR, family 2, secretin-like |
| Family | IPR003056 | GPCR, family 2, ADGRE2/ADGRE5 |
| Homologous_superfamily | IPR009030 | Growth factor receptor cysteine-rich domain superfamily |
| Homologous_superfamily | IPR046338 | GAIN domain superfamily |
| PTM | IPR000152 | EGF-type aspartate/asparagine hydroxylation site |
Domain Details Per Protein
| Protein | Additional Resources | Length | EGF-like calcium-binding, conserved site | EGF-like calcium-binding domain | EGF-like domain | EGF-type aspartate/asparagine hydroxylation site | GAIN domain superfamily | GPCR, family 2, ADGRE2/ADGRE5 | GPCR, family 2-like, 7TM | GPCR, family 2, secretin-like | GPS motif | Growth factor receptor cysteine-rich domain superfamily | NOTCH1 EGF-like calcium-binding domain |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| UniProtKB:A0A8M6Z098 | InterPro | 716 | |||||||||||
| UniProtKB:A0A8M3AUF2 | InterPro | 421 | |||||||||||
| UniProtKB:A0A8M9Q2I5 | InterPro | 727 | |||||||||||
| UniProtKB:A0A8M2B737 | InterPro | 756 | |||||||||||
| UniProtKB:A0A8M9PWR5 | InterPro | 755 | |||||||||||
| UniProtKB:A0A8M2B717 | InterPro | 473 | |||||||||||
| UniProtKB:A0AB32TM89 | InterPro | 734 |
| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA |
adgre5b.3-201
(1)
|
Ensembl | 2,298 nt |
Interactions and Pathways
No data available
Plasmids
No data available