Gene

kcnh1b

ID
ZDB-GENE-121128-4
Name
potassium voltage-gated channel, subfamily H (eag-related), member 1b
Symbol
kcnh1b Nomenclature History
Previous Names
  • zmp:0000000565 (1)
Type
protein_coding_gene
Location
Chr: 22 Mapping Details/Browsers
Description
Enables voltage-gated potassium channel activity. Acts upstream of or within hindbrain formation and somitogenesis. Predicted to be located in membrane. Predicted to be part of voltage-gated potassium channel complex. Predicted to be active in plasma membrane. Is expressed in gill; nervous system; pleuroperitoneal region; and trunk. Human ortholog(s) of this gene implicated in colorectal adenocarcinoma. Orthologous to human KCNH1 (potassium voltage-gated channel subfamily H member 1).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
1 figure from Stengel et al., 2012
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
No data available
Wild Type Expression Summary
Phenotype
All Phenotype Data
2 figures from Stengel et al., 2012
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With kcnh1b Human Ortholog
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
Temple-Baraitser syndrome 611816
Zimmermann-Laband syndrome 1 135500
1 - 2 of 2
Associated With kcnh1b Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Domain IPR000014 PAS domain
Domain IPR000595 Cyclic nucleotide-binding domain
Domain IPR000700 PAS-associated, C-terminal
Domain IPR005821 Ion transport domain
Family IPR003938 Potassium channel, voltage-dependent, EAG/ELK/ERG-like
1 - 5 of 11 Show all
Domain Details Per Protein
Protein Additional Resources Length Cyclic nucleotide-binding domain Cyclic nucleotide-binding domain superfamily Ion transport domain PAC motif PAS-associated, C-terminal PAS domain PAS domain superfamily Potassium channel, voltage-dependent, EAG Potassium channel, voltage-dependent, EAG/ELK/ERG-like Potassium channel, voltage-dependent, EAG/ELK/ERG-like, animal-type RmlC-like jelly roll fold
UniProtKB:A0A8M3AXZ2 InterPro 965
UniProtKB:K4EHU2 InterPro 956
1 - 2 of 2
Transcripts
Genome Browsers
Type Name Annotation Method Has Havana Data Length (nt) Analysis
mRNA kcnh1b-201 (1) Ensembl 2,871 nt
1 - 1 of 1
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Citations