Gene
phldb1b
- ID
- ZDB-GENE-121114-8
- Name
- pleckstrin homology-like domain, family B, member 1b
- Symbol
- phldb1b Nomenclature History
- Previous Names
- None
- Type
- protein_coding_gene
- Location
- Chr: 15 Mapping Details/Browsers
- Description
- Predicted to be active in basal cortex. Human ortholog(s) of this gene implicated in osteogenesis imperfecta. Orthologous to human PHLDB1 (pleckstrin homology like domain family B member 1).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- No data available
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| Osteogenesis imperfecta, type XXIII | 620639 |
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Domain | IPR000253 | Forkhead-associated (FHA) domain |
| Domain | IPR001849 | Pleckstrin homology domain |
| Domain | IPR037810 | PHLDB1/2/3, PH domain |
| Family | IPR052212 | Pleckstrin homology-like domain-containing protein |
| Homologous_superfamily | IPR008984 | SMAD/FHA domain superfamily |
| Homologous_superfamily | IPR011993 | PH-like domain superfamily |
Domain Details Per Protein
| Protein | Additional Resources | Length | Forkhead-associated (FHA) domain | PHLDB1/2/3, PH domain | PH-like domain superfamily | Pleckstrin homology domain | Pleckstrin homology-like domain-containing protein | SMAD/FHA domain superfamily |
|---|---|---|---|---|---|---|---|---|
| UniProtKB:A0A8M9PLG9 | InterPro | 1567 | ||||||
| UniProtKB:A0A8M9P761 | InterPro | 1472 | ||||||
| UniProtKB:A0A8M9PII3 | InterPro | 1557 | ||||||
| UniProtKB:A0A8M9PII9 | InterPro | 864 | ||||||
| UniProtKB:A0A8M9PII0 | InterPro | 1611 | ||||||
| UniProtKB:A0A8M9PCA6 | InterPro | 1466 | ||||||
| UniProtKB:A0A8M9PCA3 | InterPro | 1600 | ||||||
| UniProtKB:A0A8M9PCA0 | InterPro | 1620 | ||||||
| UniProtKB:A0A8M9PLG6 | InterPro | 1617 | ||||||
| UniProtKB:A0A8M9NYJ7 | InterPro | 1514 | ||||||
| UniProtKB:A0A8M9P758 | InterPro | 1608 | ||||||
| UniProtKB:A0A8M9NYJ3 | InterPro | 1610 | ||||||
| UniProtKB:A0A8M9PLH5 | InterPro | 927 | ||||||
| UniProtKB:A0A8M2B4B1 | InterPro | 1452 | ||||||
| UniProtKB:A0A8M9NYK0 | InterPro | 1547 | ||||||
| UniProtKB:A0A8M9P766 | InterPro | 1590 | ||||||
| UniProtKB:A0AB32T1S3 | InterPro | 1590 | ||||||
| UniProtKB:A0AB32T8P2 | InterPro | 1383 | ||||||
| UniProtKB:A0AB32T8R0 | InterPro | 1620 | ||||||
| UniProtKB:A0AB32T8R5 | InterPro | 1547 | ||||||
| UniProtKB:A0AB32TAF0 | InterPro | 1577 |
| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA |
phldb1b-201
(1)
|
Ensembl | 5,369 nt | ||
| mRNA |
phldb1b-202
(1)
|
Ensembl | 774 nt | ||
| mRNA |
phldb1b-205
(1)
|
Ensembl | 801 nt | ||
| ncRNA |
phldb1b-003
(1)
|
Ensembl | 693 nt | ||
| ncRNA |
phldb1b-004
(1)
|
Ensembl | 739 nt |
Interactions and Pathways
No data available
Plasmids
No data available