Gene

phldb1b

ID

ZDB-GENE-121114-8

Name

pleckstrin homology-like domain, family B, member 1b

Symbol

phldb1b Nomenclature History

Previous Names

None

Type

protein_coding_gene

Location

Chr: 15 Mapping Details/Browsers

Description

Predicted to be involved in regulation of microtubule cytoskeleton organization. Predicted to be active in basal cortex. Orthologous to human PHLDB1 (pleckstrin homology like domain family B member 1).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

No data available

Cross-Species Comparison

High Throughput Data

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Daniocell

Thisse Expression Data

No data available

Wild Type Expression Summary

Phenotype

All Phenotype Data: No data available
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With phldb1b Human Ortholog

Disease Ontology Term	Multi-Species Data	OMIM Term	OMIM Phenotype ID
		Osteogenesis imperfecta, type XXIII	620639

Associated With phldb1b Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Domain	IPR000253	Forkhead-associated (FHA) domain
Domain	IPR001849	Pleckstrin homology domain
Domain	IPR037810	PHLDB1/2/3, PH domain
Family	IPR052212	Pleckstrin homology-like domain-containing protein
Homologous_superfamily	IPR008984	SMAD/FHA domain superfamily
Homologous_superfamily	IPR011993	PH-like domain superfamily

Domain Details Per Protein

Protein	Length	Forkhead-associated (FHA) domain	PHLDB1/2/3, PH domain	PH-like domain superfamily	Pleckstrin homology domain	Pleckstrin homology-like domain-containing protein	SMAD/FHA domain superfamily
UniProtKB:A0A8M9PLG9 InterPro	1567
UniProtKB:A0A8M9P761 InterPro	1472
UniProtKB:A0A8M9PII3 InterPro	1557
UniProtKB:A0A8M9PII9 InterPro	864
UniProtKB:A0A8M9PII0 InterPro	1611
UniProtKB:A0A8M9PCA6 InterPro	1466
UniProtKB:A0A8M9PCA3 InterPro	1600
UniProtKB:A0A8M9PCA0 InterPro	1620
UniProtKB:A0A8M9PLG6 InterPro	1617
UniProtKB:A0A8M9NYJ7 InterPro	1514
UniProtKB:A0A8M9P758 InterPro	1608
UniProtKB:A0A8M9NYJ3 InterPro	1610
UniProtKB:A0A8M9PLH5 InterPro	927
UniProtKB:A0A8M2B4B1 InterPro	1452
UniProtKB:A0A8M9NYK0 InterPro	1547
UniProtKB:A0A8M9P766 InterPro	1590

Transcripts

Genome Browsers

NCBI

Ensembl

ZFIN

Type	Name	Annotation Method	Length (nt)	Analysis
mRNA	phldb1b-201 (1) Ensembl	Ensembl	5,369 nt	Select Tool ZFIN BLAST
mRNA	phldb1b-202 (1) Ensembl	Ensembl	774 nt	Select Tool ZFIN BLAST
mRNA	phldb1b-205 (1) Ensembl	Ensembl	801 nt	Select Tool ZFIN BLAST
ncRNA	phldb1b-003 (1) Ensembl	Ensembl	693 nt	Select Tool ZFIN BLAST
ncRNA	phldb1b-004 (1) Ensembl	Ensembl	739 nt	Select Tool ZFIN BLAST

Interactions and Pathways

No data available

Antibodies

No data available

Plasmids

No data available

Constructs

Marker Relationships

Sequences

Orthology

Comparative Orthology: Alliance
Gene Tree: Ensembl

Citations