ZFIN is now using GRCz12tu for Genomic Data
Gene
adamts17
- ID
- ZDB-GENE-121030-7
- Name
- ADAM metallopeptidase with thrombospondin type 1 motif, 17
- Symbol
- adamts17 Nomenclature History
- Previous Names
- None
- Type
- protein_coding_gene
- Location
- Chr: 7 Mapping Details/Browsers
- Genome Assembly
- GRCz12tu
- Annotation Status
- Current
- Description
- Predicted to enable metalloendopeptidase activity. Predicted to be involved in extracellular matrix organization and proteolysis. Predicted to be active in extracellular matrix. Is expressed in several structures, including digestive system; eye; heart; pleuroperitoneal region; and thymus. Human ortholog(s) of this gene implicated in Weill-Marchesani syndrome. Orthologous to human ADAMTS17 (ADAM metallopeptidase with thrombospondin type 1 motif 17).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 2 figures from Brunet et al., 2015
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| Weill-Marchesani syndrome | Alliance | Weill-Marchesani 4 syndrome, recessive | 613195 |
Domain, Family, and Site Summary
No data available
Domain Details Per Protein
| Protein | Additional Resources | Length |
|---|---|---|
| UniProtKB:A0A8M9QHG7 | InterPro | 1134 |
| UniProtKB:A0AC58G343 | InterPro | 1134 |
| UniProtKB:A0AC58G347 | InterPro | 1109 |
| UniProtKB:A0AC58G361 | InterPro | 812 |
| UniProtKB:A0AC58G364 | InterPro | 787 |
- Genome Browsers
| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA |
adamts17-201
(1)
|
Ensembl | 3,150 nt | ||
| mRNA |
adamts17-202
(1)
|
Ensembl | 3,069 nt |
Interactions and Pathways
No data available
Plasmids
No data available
- Genome Browsers