Gene
rxfp3.3a1
- ID
- ZDB-GENE-121030-1
- Name
- relaxin family peptide receptor 3.3a1
- Symbol
- rxfp3.3a1 Nomenclature History
- Previous Names
-
- rxfp3-3a1 (1)
- Type
- protein_coding_gene
- Location
- Chr: 7 Mapping Details/Browsers
- Description
- Predicted to enable C-C chemokine binding activity and C-C chemokine receptor activity. Predicted to be involved in several processes, including calcium-mediated signaling; cell chemotaxis; and positive regulation of cytosolic calcium ion concentration. Predicted to act upstream of or within G protein-coupled receptor signaling pathway. Predicted to be located in membrane. Predicted to be active in external side of plasma membrane. Is expressed in female organism and male organism.
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 2 figures from 2 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
| Allele | Type | Localization | Consequence | Mutagen | Supplier |
|---|---|---|---|---|---|
| sa40942 | Allele with one point mutation | Unknown | Splice Site | ENU |
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No data available
Human Disease
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Additional Resources | Length | Angiotensin II receptor family | C-C chemokine receptor type 1-9-like | GPCR, rhodopsin-like, 7TM | G protein-coupled receptor, rhodopsin-like |
|---|---|---|---|---|---|---|
| UniProtKB:F1QQH4 | InterPro | 339 |
| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA |
rxfp3.3a1-201
(1)
|
Ensembl | 1,523 nt |
Interactions and Pathways
No data available
Plasmids
No data available
No data available
| Relationship | Marker Type | Marker | Accession Numbers | Citations |
|---|---|---|---|---|
| Contained in | BAC | DKEY-106F13 | ZFIN Curated Data |
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| Type | Accession # | Sequence | Length (nt/aa) | Analysis |
|---|---|---|---|---|
| RNA | RefSeq:XM_005168953 (1) | 2079 nt | ||
| Genomic | GenBank:BX511006 (1) | 220514 nt | ||
| Polypeptide | UniProtKB:F1QQH4 (1) | 339 aa |
No data available
- Alnafea, H., Vahkal, B., Zelmer, C.K., Yegorov, S., Bogerd, J., Good, S.V. (2019) Japanese medaka as a model for studying the relaxin family genes involved in neuroendocrine regulation: Insights from the expression of fish-specific rln3 and insl5 and rxfp3/4-type receptor paralogues. Molecular and Cellular Endocrinology. 487:2-11
- Donizetti, A., Fiengo, M., Iazzetti, G., Del Gaudio, R., Di Giaimo, R., Pariante, P., Minucci, S., Aniello, F. (2015) Expression analysis of five zebrafish rxfp3 homologues reveals evolutionary conservation of gene expression pattern. Journal of experimental zoology. Part B, Molecular and developmental evolution. 324(1):22-9
- Good, S., Yegorov, S., Martijn, J., Franck, J., and Bogerd, J. (2012) New insights into ligand-receptor pairing and coevolution of relaxin family peptides and their receptors in teleosts. International Journal of Evolutionary Biology. 2012:310278
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