Gene

xrcc2

ID
ZDB-GENE-121029-1
Name
X-ray repair complementing defective repair in Chinese hamster cells 2
Symbol
xrcc2 Nomenclature History
Previous Names
None
Type
protein_coding_gene
Location
Chr: 24 Mapping Details/Browsers
Description
Predicted to have ATP binding activity; DNA binding activity; and DNA-dependent ATPase activity. Predicted to be involved in double-strand break repair via homologous recombination. Predicted to localize to Rad51B-Rad51C-Rad51D-XRCC2 complex and replication fork. Human ortholog(s) of this gene implicated in Fanconi anemia complementation group U and pancreatic cancer. Orthologous to human XRCC2 (X-ray repair cross complementing 2).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
No data available
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
No data available
Wild Type Expression Summary
Phenotype
All Phenotype Data
No data available
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With xrcc2 Human Ortholog
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
Fanconi anemia complementation group U Alliance ?Fanconi anemia, complementation group U 617247
primary ovarian insufficiency 17 Alliance ?Premature ovarian failure 17 619146
spermatogenic failure 50 Alliance Spermatogenic failure 50 619145
Associated With xrcc2 Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
No data available
Domain Details Per Protein
No data available
Transcripts
Genome Browsers
No data available
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Citations