Gene
acsf3
- ID
- ZDB-GENE-121026-3
- Name
- acyl-CoA synthetase family member 3
- Symbol
- acsf3 Nomenclature History
- Previous Names
- None
- Type
- protein_coding_gene
- Location
- Chr: 7 Mapping Details/Browsers
- Description
- Human ortholog(s) of this gene implicated in combined malonic and methylmalonic acidemia. Orthologous to human ACSF3 (acyl-CoA synthetase family member 3).
- Genome Resources
-
- Alliance (1)
- Gene:562292 (1)
- Note
- None
- Comparative Information
-
- All Expression Data
- No data available
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| combined malonic and methylmalonic acidemia | Alliance | Combined malonic and methylmalonic aciduria | 614265 |
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Conserved_site | IPR020845 | AMP-binding, conserved site |
| Domain | IPR000873 | AMP-dependent synthetase/ligase domain |
| Domain | IPR025110 | AMP-binding enzyme, C-terminal domain |
| Homologous_superfamily | IPR042099 | ANL, N-terminal domain |
| Homologous_superfamily | IPR045851 | AMP-binding enzyme, C-terminal domain superfamily |
Domain Details Per Protein
| Protein | Length | AMP-binding, conserved site | AMP-binding enzyme, C-terminal domain | AMP-binding enzyme, C-terminal domain superfamily | AMP-dependent synthetase/ligase domain | ANL, N-terminal domain |
|---|---|---|---|---|---|---|
|
UniProtKB:A0A2R8QA86
|
579 | |||||
|
UniProtKB:E7F2S8
|
579 | |||||
|
UniProtKB:A0A2R8QFY7
|
579 |
- Genome Browsers
Interactions and Pathways
No data available
Plasmids
No data available
- Comparative Orthology
- Alliance