Gene
gucy1a2
- ID
- ZDB-GENE-121023-3
- Name
- guanylate cyclase 1, soluble, alpha 2
- Symbol
- gucy1a2 Nomenclature History
- Previous Names
- None
- Type
- protein_coding_gene
- Location
- Chr: 15 Mapping Details/Browsers
- Description
- Predicted to enable guanylate cyclase activity. Predicted to be involved in cGMP-mediated signaling and response to oxygen levels. Predicted to act upstream of or within cGMP biosynthetic process and intracellular signal transduction. Predicted to be located in cytoplasm. Predicted to be part of guanylate cyclase complex, soluble. Is expressed in ovary. Orthologous to human GUCY1A2 (guanylate cyclase 1 soluble subunit alpha 2).
- Genome Resources
-
- Alliance (1)
- Gene:100330875 (1)
- Note
- None
- Comparative Information
-
- All Expression Data
- 1 figure from Li et al., 2018
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Conserved_site | IPR018297 | Adenylyl cyclase class-4/guanylyl cyclase, conserved site |
| Domain | IPR001054 | Adenylyl cyclase class-3/4/guanylyl cyclase |
| Domain | IPR011645 | Haem NO binding associated |
| Homologous_superfamily | IPR024096 | NO signalling/Golgi transport ligand-binding domain superfamily |
| Homologous_superfamily | IPR029787 | Nucleotide cyclase |
| Homologous_superfamily | IPR038158 | H-NOX domain superfamily |
| Homologous_superfamily | IPR042463 | Haem NO binding associated domain superfamily |
Domain Details Per Protein
| Protein | Length | Adenylyl cyclase class-3/4/guanylyl cyclase | Adenylyl cyclase class-4/guanylyl cyclase, conserved site | Haem NO binding associated | Haem NO binding associated domain superfamily | H-NOX domain superfamily | NO signalling/Golgi transport ligand-binding domain superfamily | Nucleotide cyclase |
|---|---|---|---|---|---|---|---|---|
|
UniProtKB:A0A8M3AT28
|
608 |
- Genome Browsers
Interactions and Pathways
No data available
Plasmids
No data available
- Comparative Orthology
- Alliance