Gene

sting1

ID
ZDB-GENE-120921-1
Name
stimulator of interferon response cGAMP interactor 1
Symbol
sting1 Nomenclature History
Previous Names
  • MITA (1)
  • STING (1)
  • ERIS (1)
  • MPYS (1)
  • tmem173
Type
protein_coding_gene
Location
Chr: 14 Mapping Details/Browsers
Description
Predicted to have cyclic-GMP-AMP binding activity and cyclic-di-GMP binding activity. Involved in several processes, including NIK/NF-kappaB signaling; defense response to other organism; and positive regulation of defense response to virus by host. Localizes to endoplasmic reticulum. Human ortholog(s) of this gene implicated in STING-associated vasculopathy with onset in infancy. Orthologous to human STING1 (stimulator of interferon response cGAMP interactor 1).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
2 figures from Liu et al., 2020
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
No data available
Wild Type Expression Summary
Phenotype
All Phenotype Data
2 figures from 2 publications
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With sting1 Human Ortholog
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
STING-associated vasculopathy with onset in infancy Alliance STING-associated vasculopathy, infantile-onset 615934
Associated With sting1 Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Domain IPR033952 Stimulator of interferon genes protein, C-terminal
Family IPR029158 Stimulator of interferon genes protein
Homologous_superfamily IPR038623 Stimulator of interferon genes protein, C-terminal domain superfamily
Domain Details Per Protein
Protein Length Stimulator of interferon genes protein Stimulator of interferon genes protein, C-terminal Stimulator of interferon genes protein, C-terminal domain superfamily
UniProtKB:E7F4N7 398
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations