tnfrsf11a

ID

ZDB-GENE-120910-2

Name

tumor necrosis factor receptor superfamily, member 11a, NFKB activator

Symbol

tnfrsf11a Nomenclature History

Previous Names

None

Type

protein_coding_gene

Location

Chr: 24 Mapping Details/Browsers

Genome Assembly

GRCz12tu

Annotation Status

Current

Description

Predicted to be located in membrane. Human ortholog(s) of this gene implicated in bone development disease and bone remodeling disease (multiple). Orthologous to human TNFRSF11A (TNF receptor superfamily member 11a).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

No data available

Cross-Species Comparison

High Throughput Data

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Daniocell

Thisse Expression Data

No data available

Wild Type Expression Summary

Phenotype

All Phenotype Data: No data available
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With tnfrsf11a Human Ortholog

Disease Ontology Term	Multi-Species Data	OMIM Term	OMIM Phenotype ID
autosomal recessive osteopetrosis 7	Alliance	Osteopetrosis, autosomal recessive 7	612301
familial expansile osteolysis	Alliance	Osteolysis, familial expansile	174810
Paget's disease of bone 2	Alliance	{Paget disease of bone 2, early-onset}	602080

Associated With tnfrsf11a Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Domain	IPR001368	TNFR/NGFR cysteine-rich region
Family	IPR053075	Tumor necrosis factor receptor superfamily member 11A

Domain Details Per Protein

Protein	Additional Resources	Length
UniProtKB:A0A8M9PE80	InterPro	497
UniProtKB:A0A8M3AVZ3	InterPro	497
UniProtKB:E7F027	InterPro	574
UniProtKB:A0A8M9P635	InterPro	506
UniProtKB:A0A8M9Q403	InterPro	506
UniProtKB:A0A8M9PQZ0	InterPro	236
UniProtKB:A0A8M9Q849	InterPro	574
UniProtKB:A0A8M3ANI1	InterPro	236