Gene
muc2.1
- ID
- ZDB-GENE-120904-2
- Name
- mucin 2.1
- Symbol
- muc2.1 Nomenclature History
- Previous Names
-
- muc2l1
- Type
- protein_coding_gene
- Location
- Chr: 25 Mapping Details/Browsers
- Description
- Predicted to be located in extracellular region. Predicted to be active in extracellular matrix and extracellular space. Is expressed in gut and intestine. Human ortholog(s) of this gene implicated in asthma. Orthologous to human MUC2 (mucin 2, oligomeric mucus/gel-forming).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 8 figures from 7 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
No data available
Domain Details Per Protein
| Protein | Additional Resources | Length |
|---|---|---|
| UniProtKB:A0A8M9P711 | InterPro | 612 |
| UniProtKB:A0A8M9PVR3 | InterPro | 742 |
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- Genome Browsers
Interactions and Pathways
No data available
Plasmids
No data available
- Liao, X., Lan, Y., Wang, W., Zhang, J., Shao, R., Yin, Z., Gudmundsson, G.H., Bergman, P., Mai, K., Ai, Q., Wan, M. (2023) Vitamin D influences gut microbiota and acetate production in zebrafish (Danio rerio) to promote intestinal immunity against invading pathogens. Gut microbes. 15:21875752187575
- Ni, Y., Zhang, Y., Zheng, L., Rong, N., Yang, Y., Gong, P., Yang, Y., Siwu, X., Zhang, C., Zhu, L., Fu, Z. (2023) Bifidobacterium and Lactobacillus improve inflammatory bowel disease in zebrafish of different ages by regulating the intestinal mucosal barrier and microbiota. Life sciences. 324:121699
- Rawling, M., Schiavone, M., Mugnier, A., Leclercq, E., Merrifield, D., Foey, A., Apper, E. (2023) Modulation of Zebrafish (Danio rerio) Intestinal Mucosal Barrier Function Fed Different Postbiotics and a Probiotic from Lactobacilli. Microorganisms. 11(12):
- Yang, Y., Du, H., Pan, Y., Gong, P., Yang, Y., Wu, F., Pan, D., Xie, W., Fu, Z., Ni, Y. (2023) Bifidobacterium animalis subsp. lactis LKM512 alleviates inflammatory bowel disease in larval zebrafish by reshaping microbiota. Biological & pharmaceutical bulletin. 46(12):1706-1713
- Yue, Z., Fan, Z., Zhang, H., Feng, B., Wu, C., Chen, S., Ouyang, J., Fan, H., Weng, P., Feng, H., Chen, S., Dong, M., Xu, A., Huang, S. (2023) Differential roles of the fish chitinous membrane in gut barrier immunity and digestive compartments. EMBO reports. 24(4):e56645
- Zhang, C., Zhao, Z., Jia, Y.J., Zhang, P.Q., Sun, Y., Zhou, Y.C., Wang, G.X., Zhu, B. (2023) Rationally Designed Self-Assembling Nanovaccines Elicit Robust Mucosal and Systemic Immunity against Rhabdovirus. ACS applied materials & interfaces. 16(1):228-244
- Edirisinghe, S.L., Nikapitiya, C., Dananjaya, S.H.S., Park, J., Kim, D., Choi, D., De Zoysa, M. (2022) Effect of Polydeoxyribonucleotide (PDRN) Treatment on Corneal Wound Healing in Zebrafish (Danio rerio). International Journal of Molecular Sciences. 23(21):
- Lai, C.Y., Yeh, K.Y., Liu, B.F., Chang, T.M., Chang, C.H., Liao, Y.F., Liu, Y.W., Her, G.M. (2021) MicroRNA-21 Plays Multiple Oncometabolic Roles in Colitis-Associated Carcinoma and Colorectal Cancer via the PI3K/AKT, STAT3, and PDCD4/TNF-α Signaling Pathways in Zebrafish. Cancers. 13(21):
- Luo, T., Wang, X., Jin, Y. (2021) Low concentrations of imidacloprid exposure induced gut toxicity in adult zebrafish (Danio rerio). Comparative biochemistry and physiology. Toxicology & pharmacology : CBP. 241:108972
- Qian, M., Wang, J., Ji, X., Yang, H., Tang, B., Zhang, H., Yang, G., Bao, Z., Jin, Y. (2021) Sub-chronic exposure to antibiotics doxycycline, oxytetracycline or florfenicol impacts gut barrier and induces gut microbiota dysbiosis in adult zebrafish (Daino rerio). Ecotoxicology and environmental safety. 221:112464
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